ArticleBMJ open2016
Screening of gestational diabetes mellitus in early pregnancy by oral glucose tolerance test and glycosylated fibronectin: study protocol for an international, prospective, multicentre cohort trial.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02035059 (Predictability of Gestational Diabetes Mellitus in First and Second Trimester, Using Novel Biomarkers, and the Development of New Biomarkers by Quantitative Proteomic Analysis), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Predictability of Gestational Diabetes Mellitus in First and Second Trimester, Using Novel Biomarkers, and the Development of New Biomarkers by Quantitative Proteomic Analysis
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Glycosylated fibronectin: a maternal serum biomarker for diagnosing gestational diabetes mellitus.Anatomy & cell biology · 2026Article
- The utility of early gestational OGTT and biomarkers for the development of gestational diabetes mellitus: an international prospective multicentre cohort study.Diabetologia · 2025Observational
- Early prediction of gestational diabetes mellitus: the role of the pregnancy-specific triglycerides-glucose index and other fasting parameters in combination with dynamic testing.Acta diabetologica · 2025Article
- Glycosylated fibronectin as a biomarker to predict gestational diabetes mellitus in the first trimester of pregnancy.Journal of family medicine and primary care · 2025Article
- Assessment of maternal and neonatal outcomes in pregnant women with and without gestational diabetes mellitus diagnosed at the three trimesters of pregnancy: a cross-sectional study in a hospital in Northeast Mexico.The Pan African medical journal · 2025Article
- Early prediction of gestational diabetes mellitus using first trimester maternal serum pregnancy-associated plasma protein-a: A cross-sectional study.Health science reports · 2024Article
- Prediction of gestational diabetes mellitus by multiple biomarkers at early gestation.BMC pregnancy and childbirth · 2024Article
- Article
- New Developments, Challenges and Open Questions in Diagnosis and Treatment of Gestational Diabetes Mellitus.Journal of clinical medicine · 2022Article
- The diagnostic model for early detection of gestational diabetes mellitus and gestational diabetic nephropathy.Journal of clinical laboratory analysis · 2022Article
- Neurodevelopmental Outcomes at 18 Months of Corrected Age for Late Preterm Infants Born at 34 and 35 Gestational Weeks.International journal of environmental research and public health · 2021Article
- Antioxidant activities of Dhanwantaram Kashayam -an Ayurvedic poly herbal formulation alleviates diabetic complications in rats.Journal of diabetes and metabolic disorders · 2020Article
- Glycosylated fibronectin as a first trimester marker for gestational diabetes.Archives of gynecology and obstetrics · 2020Article
- The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats.Nutrition & metabolism · 2018Article
- Early Pregnancy Biochemical Predictors of Gestational Diabetes Mellitus.Current diabetes reports · 2017Review
- High Fasting Plasma Glucose during Early Pregnancy: A Review about Early Gestational Diabetes Mellitus.Journal of diabetes research · 2017Review
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAs the accurate diagnosis and treatment of gestational diabetes mellitus (GDM) is of increasing importance; new diagnostic approaches for the assessment of GDM in early pregnancy were recently suggested. We evaluate the diagnostic power of an 'early' oral glucose tolerance test (OGTT) 75 g and glycosylated fibronectin (glyFn) for GDM screening in a normal cohort. METHODS AND ANALYSIS: In a prospective cohort study, 748 singleton pregnancies are recruited in 6 centres in Switzerland, Austria and Germany. Women are screened for pre-existing diabetes mellitus and GDM by an 'early' OGTT 75 g and/or the new biomarker, glyFn, at 12-15 weeks of gestation. Different screening strategies are compared to evaluate the impact on detection of GDM by an OGTT 75 g at 24-28 weeks of gestation as recommended by the International Association of Diabetes and Pregnancy Study Groups (IADPSG). A new screening algorithm is created by using multivariable risk estimation based on 'early' OGTT 75 g and/or glyFn results, incorporating maternal risk factors. Recruitment began in May 2014. ETHICS AND DISSEMINATION: This study received ethical approval from the ethics committees in Basel, Zurich, Vienna, Salzburg and Freiburg. It was registered under http://www.ClinicalTrials.gov (NCT02035059) on 12 January 2014. Data will be presented at international conferences and published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT02035059.
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