SynthesisBMJ (Clinical research ed.)2016
Antenatal corticosteroids for maturity of term or near term fetuses: systematic review and meta-analysis of randomized controlled trials.
Synthesis in BMJ (Clinical research ed.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06188195 (Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for Neonatal Acute Respiratory Distress Syndrome), which is not on this map. Cited by 64 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for Neonatal Acute Respiratory Distress Syndrome
Who cites it
64 citing papers in PubMed, 7 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- Factors influencing appropriate use of interventions for management of women experiencing preterm birth: A mixed-methods systematic review and narrative synthesis.PLoS medicine · 2022Pooled it
- Interventions for the management of transient tachypnoea of the newborn - an overview of systematic reviews.The Cochrane database of systematic reviews · 2022Pooled it
- Antenatal corticosteroids prior to planned caesarean at term for improving neonatal outcomes.The Cochrane database of systematic reviews · 2021Pooled it
- Antenatal corticosteroids for impending late preterm (34-36+6 weeks) deliveries-A systematic review and meta-analysis of RCTs.PloS one · 2021Pooled it
- Long-term neuropathological and/or neurobehavioral effects of antenatal corticosteroid therapy in animal models: a systematic review.Pediatric research · 2020Pooled it
- Strategies for optimising antenatal corticosteroid administration for women with anticipated preterm birth.The Cochrane database of systematic reviews · 2020Pooled it
- Postnatal corticosteroids for transient tachypnoea of the newborn.The Cochrane database of systematic reviews · 2020Pooled it
- Trial
- Glucocorticoids in pregnancy: a master-switch for fetal maturation.Endocrine reviews · 2026Review
- Antenatal corticosteroid administration-to-delivery intervals and neonatal outcomes in late preterm labor: a historical cohort study.BMC pregnancy and childbirth · 2026Article
- Fetal Growth Restriction: Contemporary Evidence to Guide Delivery Timing and Intrapartum Management.Diagnostics (Basel, Switzerland) · 2026Review
- Association between in vitro fertilization and severe neonatal morbidity.Journal of assisted reproduction and genetics · 2026Article
- Article
- Antenatal Corticosteroid Administration and Childhood Respiratory Morbidity: A Regression Discontinuity Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Antenatal Corticosteroids and Infectious Diseases Throughout Childhood.JAMA network open · 2025Article
- Impact of antenatal corticosteroid therapy on neonatal respiratory outcomes in late preterm births.BMC pediatrics · 2025Article
- Long-Term Neurodevelopmental Outcomes After Antenatal Corticosteroid Therapy in Late Preterm Twins: A Nationwide Retrospective Cohort Study.Journal of Korean medical science · 2025Article
- Respiratory distress in late-preterm neonates: from controversy to consensus - a survey of regional advisory boards and neonatologists in France.BMJ paediatrics open · 2025Article
- Mode of delivery among preterm twins and offspring health, a retrospective cohort study.European journal of pediatrics · 2025Article
- A comparison of short- and long-term prognoses between cases with and without antenatal corticosteroid administration in late preterm delivery: a nationwide population-based study.BMC pregnancy and childbirth · 2025Observational
4 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of antenatal corticosteroids given at ≥34 weeks' gestation.
designSystematic review with meta-analysis. DATA SOURCES: Electronic databases were searched from their inception to February 2016. ELIGIBILITY CRITERIA FOR STUDY SELECTION: Randomized clinical trials comparing antenatal corticosteroids with placebo or no treatment in women with a singleton pregnancy at ≥34 weeks' gestation. Trials on antenatal steroids in women expected to deliver late preterm (34 DATA SYNTHESIS: The primary outcome was the incidence of severe respiratory distress syndrome (RDS). The summary measures were reported as relative risks or mean differences with 95% confidence intervals.
resultsSix trials, including 5698 singleton pregnancies, were analyzed. Three included 3200 women at 34
conclusionsAntenatal steroids at ≥34 weeks' gestation reduce neonatal respiratory morbidity. A single course of corticosteroids can be considered for women at risk of imminent late premature delivery 34 SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016035234.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.