Evidence map›Paper›PMID 27733208›Full record

ArticleChinese journal of cancer2016

ABO blood group is a predictor of survival in patients with laryngeal cancer.

Ting Jin, Pei-Jing Li, Xiao-Zhong Chen, Wei-Han Hu

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Article in Chinese journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

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9citing papers in PubMed
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3 · Its place in the literature

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9 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ting JinKey Laboratory of Radiation Oncology in Zhejiang Province, Hangzhou, 310022, Zhejiang, P. R. China.
Pei-Jing LiState Key Laboratory of Oncology in South China, Department of Radiation Oncology, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, P. R. China.
Xiao-Zhong ChenKey Laboratory of Radiation Oncology in Zhejiang Province, Hangzhou, 310022, Zhejiang, P. R. China. chenxiaozhongfy@163.com.
Wei-Han HuState Key Laboratory of Oncology in South China, Department of Radiation Oncology, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, P. R. China. huwh@sysucc.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether the ABO blood group is associated with the survival of patients with laryngeal cancer remains unknown. The purpose of this study was to investigate the association between the ABO blood group and clinicopathologic characteristics of patients with laryngeal cancer and assess whether the ABO blood group was associated with prognosis.

methodsWe analyzed the records of 1260 patients with laryngeal cancer who underwent curative treatment at Sun Yat-sen University Cancer Center between January 1993 and December 2009. The Chi-square test was used to assess the relationship between the ABO blood group and clinicopathologic characteristics. The Kaplan-Meier method was used to estimate 3-, 5-, and 10-year overall survival (OS) rates. The Cox proportional hazards model was used in univariate and multivariate analyses of OS.

resultsNo significant association was found between the ABO blood group and clinicopathologic characteristics except for primary tumor site. The median OS for patients with blood groups A, B, AB, and O were 87.0, 80.0, 90.0, and 72.5 months, respectively. The 3-, 5-, and 10-year OS rates were 82.4%, 76.0%, and 67.5% for patients with blood group A; 77.4%, 69.8%, and 58.4% for patients with blood group B; 82.2%, 73.1%, and 65.6% for patients with blood group AB; and 71.7%, 66.4%, and 55.5% for patients with blood group O, respectively. Univariate and multivariate analyses showed that the ABO blood group had significant effects on prognosis in patients with laryngeal cancer.

conclusionsThe ABO blood group is associated with survival in patients with laryngeal cancer. Patients with blood group O had significantly shorter OS than patients with other ABO blood groups.

Indexed as

ABO Blood-Group SystemAdultAgedAged, 80 and overBiomarkers, TumorCombined Modality TherapyFemaleFollow-Up StudiesHumansLaryngeal NeoplasmsMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesSurvival RateABO Blood-Group SystemBiomarkers, TumorLaryngeal cancerPrognosisSurvivalThe ABO blood group

Identifiers

PMID27733208
PMCPMC5062923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.