ArticleBMC research notes2016
The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework.
Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Effect of Caregiver Training on the Neurodevelopment of HIV-Exposed Uninfected Children and Caregiver Mental Health: A Ugandan Cluster-Randomized Controlled Trial.Journal of developmental and behavioral pediatrics : JDBPTrial
- Maternal ART throughout gestation prevents caudate volume reductions in neonates who are HIV exposed but uninfected.Frontiers in neuroscience · 2023Article
- Congenital Cytomegalovirus and Human Immunodeficiency Virus: Effects on Hearing, Speech and Language Development, and Clinical Outcomes in Children.Frontiers in pediatrics · 2021Review
- Neurodevelopment of HIV-exposed uninfected children in South Africa: outcomes from an observational birth cohort study.The Lancet. Child & adolescent health · 2019Observational
- [Neuropsychological development of human immunodeficiency virus-exposed uninfected infants/young children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsArticle
- Measurement of expressive vocabulary in school-age children: Development and application of the Kilifi Naming Test (KNT).Applied neuropsychology. ChildArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundHIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.
methodsWe compared language development in children exposed to HIV in utero to community controls (N = 262, 8-30 months) in rural Kenya, using locally adapted and validated communicative development inventories.
resultsThe mean score of the younger HIV-exposed uninfected infants (8-15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.
conclusionsOur preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.
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