Who was studied, and how
Five numbers in the abstract
Where each one falls
Where it lands on the map
What it changes
Among 3 other studies
2,866people with kidney disease, in this paper
The trial randomly assignedassigned by chance
statin
placebo
Lowered albuminuria−0.46
Lowered urinary albumin excretion rates−1.68
randomisedAmong subjects with urinary protein excretion 30 to 300 mg/day, the trial randomly assignedassigned by chance
statin
placebo
May have lowered albuminuria−0.71
randomised · one subgroupthe abstract, start to end
… in the statin group were reduced by 0.46 [95 % confidence interval (CI),-0.68 to -0.25, P < 0.0001] and 1.68 (95 % CI, -3.23 to -0.12, …
… with pathologic albuminuria: change of -0.71 (95 % CI, -1.09 to -0.33, …
… [standardized mean difference (SMD), -0.56; 95 % CI, -0.80 to -0.32, P < 0.00001] and the decrease was significant during the 1 to 3 years period of statin therapy (SMD, -0.57; 95 % CI, -0.95 to -0.19, …
← favours treatmentfavours comparator →
could be chanceAlbuminuriastatin vs placebo
−0.46−0.68 to −0.25
Albuminuriastatin vs placebo, in subjects with urinary protein excretion 30 to 300 mg/day
−0.71−1.09 to −0.33
Albuminuriastatin vs placebo, in patients of type 2 diabetes mellitus with diabetic nephropathy
−0.56−0.80 to −0.32
Urinary albumin excretion ratesstatin vs placebo
−1.68−3.23 to −0.12
Albuminuriastatin vs placebo, in 1 to 3 years period of statin therapy
−0.57−0.95 to −0.19
StatinsKidney outcomes
Statins × kidney outcomeshelps?mixed
unlikelylikely
0.00not counted
← favours treatmentfavours comparator →
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