Evidence map›Paper›PMID 27733150›Full record

ArticleBMC veterinary research2016

Pathological and immunological characteristics of piglets infected experimentally with a HP-PRRSV TJ strain.

Zhenguang Li, Yanliang He, Xiaoqin Xu, Xue Leng, Shufen Li, Yongjun Wen, Fengxue Wang, Mingqi Xia, Shipeng Cheng, Hua Wu

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

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  8. Natural co-infection of pigs with African swine fever virus and porcine reproductive and respiratory syndrome virus in India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
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  15. A New Porcine Reproductive and Respiratory Syndrome Virus withTransboundary and emerging diseases · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Effect of EthanolicVeterinary sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhenguang LiSinovet (Beijing) Biotechnology Co., Ltd., Kaituo Road 5, Haidian District, Beijing, 100085, China.
Yanliang HeSinovet (Beijing) Biotechnology Co., Ltd., Kaituo Road 5, Haidian District, Beijing, 100085, China.
Xiaoqin XuJiangyan Animal Health Inspection Institute, Jiangguan Road 251, Taizhou, Jiangsu, 225529, China.
Xue LengState Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences,, Juye Street 4899, Changchun, Jilin, 130122, China.
Shufen LiSinovet (Beijing) Biotechnology Co., Ltd., Kaituo Road 5, Haidian District, Beijing, 100085, China.
Yongjun WenState Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences,, Juye Street 4899, Changchun, Jilin, 130122, China.
Fengxue WangState Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences,, Juye Street 4899, Changchun, Jilin, 130122, China.
Mingqi XiaSinovet (Beijing) Biotechnology Co., Ltd., Kaituo Road 5, Haidian District, Beijing, 100085, China.
Shipeng ChengState Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences,, Juye Street 4899, Changchun, Jilin, 130122, China.
Hua WuSinovet (Beijing) Biotechnology Co., Ltd., Kaituo Road 5, Haidian District, Beijing, 100085, China. wuhua@sinovetah.com.
Sinovac Biotech · CNChinese Academy of Agricultural Sciences · CNInstitute of Special Animal and Plant Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine reproductive and respiratory syndrome (PRRS) remains a major threat to swine industry all over the world. The aim of this study was to investigate the mechanism of pathogenesis and immune responses caused by a highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV).

resultsAll piglets experimentally infected with a HP-PRRSV TJ strain virus developed typical clinical signs of PRRS. The percentages of CD3

conclusionsThese results clearly indicated that HP-PRRSV TJ strain infection would activate host humoral immune response at the early period post infection and cause severe pathological damages on lungs and inhibit cellular immune response after infection.

Indexed as

Immunity, CellularImmunity, HumoralAnimalsAntibodies, ViralLungLymphocytesPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusSwineAntibodies, Viralcell-mediated immunityHP-PRRSVhumoral immunityimmune responses

Identifiers

PMID27733150
PMCPMC5062860
OpenAlexW2530751773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.