ReviewJournal of stroke2016
Post-stroke Mood and Emotional Disturbances: Pharmacological Therapy Based on Mechanisms.
Review in Journal of stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05822986 (The Validity and Reliability of the Turkish Version of the Testing Emotionalism After Recent Stroke - Questionnaire), which is not on this map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Validity and Reliability of the Turkish Version of the Testing Emotionalism After Recent Stroke - Questionnaire (TEARS-Q)
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pharmacological, non-invasive brain stimulation and psychological interventions, and their combination, for treating depression after stroke.The Cochrane database of systematic reviews · 2023Pooled it
- Pharmacological, psychological, and non-invasive brain stimulation interventions for treating depression after stroke.The Cochrane database of systematic reviews · 2020Pooled it
- Dynamic Hemispheric Lateralization of Naturalistic Emotional Processing After Unilateral Stroke: An EEG Study.CNS neuroscience & therapeutics · 2026Article
- Evaluating the Psychometric Properties of the Indonesian Version of the Stroke Stigma Scale Among Indonesian Stroke Survivors.International journal of environmental research and public health · 2026Article
- Prevalence of depression and cognitive impairment and their inter-relationship and association with quality of life among older stroke survivors: the findings of a national survey in China.Stroke and vascular neurology · 2026Article
- Characterising Challenging Behaviour Following Stroke: A Retrospective Chart Review of Presentation, Management, and Outcomes.Nursing reports (Pavia, Italy) · 2026Article
- Traditional Rehabilitation Experiences, Unmet Needs, and Perspectives on Virtual Reality-Based Rehabilitation Among Patients With Stroke in China: Qualitative Thematic Analysis and Semistructured Interview Study.Journal of medical Internet research · 2026Article
- Effects of intermittent theta-burst stimulation (iTBS) on post-stroke depression (PSD): A study protocol for a single-center randomized controlled trial.Contemporary clinical trials communications · 2026Article
- Exploring the neuroprotective effects of phytocannabinoids on oxygen-glucose deprived neurons in an in vitro model of stroke.Journal of cannabis research · 2026Article
- Article
- Commentary: Identifying key predictors of post-stroke depression and cognitive impairment in acute stroke survivors.Frontiers in neurology · 2026Article
- Brain-Behavior Relationships: Neural Mechanisms of Impulsivity and Compulsivity in Neuropsychiatric Disorders.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2025Review
- Stroke Survivors Have Almost Three Times Higher Risk of Depression: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Modern Technologies Supporting Motor Rehabilitation After Stroke: A Narrative Review.Journal of clinical medicine · 2025Review
- Effects of Combining Traditional East Asian and Conventional Western Medicine on Acute Stroke Outcomes.Journal of the American Heart Association · 2025Article
- "The stroke has already happened. You can't undo what has happened" emotions, coping, and adjustment in the experiences of southeast Asian people living with stroke - A qualitative study.Preventive medicine reports · 2025Article
- Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study.Scientific reports · 2025Article
- Post-Stroke Recovery: A Review of Hydrogel-Based Phytochemical Delivery Systems.Gels (Basel, Switzerland) · 2025Review
- Analysis of factors affecting acute fatigue in patients with acute ischemic stroke: A single-center study from China.Clinics (Sao Paulo, Brazil) · 2025Article
- Abnormalities of lipid metabolism in the progression and treatment of depression.Frontiers in psychiatry · 2025Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Out of the many post-stroke disturbances, post-stroke depression, post-stroke anxiety, post-stroke emotional incontinence, post-stroke anger proneness, and post-stroke fatigue are frequent and important symptoms. These symptoms are distressing for both the patients and their caregivers, and negatively influence the patient's quality of life. Unfortunately, these emotional disturbances are not apparent and are therefore often unnoticed by busy clinicians. Their phenomenology, predicting factors, and pathophysiology have been under-studied, and are under-recognized. In addition, well-designed clinical trials regarding these symptoms are rare. Fortunately, these mood and emotional disturbances may be treated or prevented by various methods, including pharmacological therapy. To administer the appropriate therapy, we have to understand the phenomenology and the similarities and differences in the pathophysiological mechanisms associated with these emotional symptoms. This narrative review will describe some of the most common or relevant post-stroke mood and emotional disturbances. The phenomenology, factors or predictors, and relevant lesion locations will be described, and pharmacological treatment of these emotional disturbances will be discussed based on presumable pathophysiological mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.