ArticleJournal of stroke2016
Difference in the Location and Risk Factors of Cerebral Microbleeds According to Ischemic Stroke Subtypes.
Article in Journal of stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of anticoagulant therapy and cerebral microbleeds: a systematic review and meta-analysis.Journal of neurology · 2021Pooled it
- Prevalence and Risk Factors for Cerebral Microbleeds in Chinese Patients With Acute Ischemic Stroke.Brain and behavior · 2026Article
- Prognostic analysis of cerebral microbleeds in patients with large artery atherosclerotic stroke without thrombolytic therapy.European journal of medical research · 2025Article
- Prospective study of primary aldosteronism in acute ischemic stroke: association with small vessel disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Overview and Future Direction of Embolic Stroke of Undetermined Source from the Insights of CHALLENGE ESUS/CS Registry.Journal of atherosclerosis and thrombosis · 2024Review
- Cerebral Small Vessel Disease.International journal of molecular sciences · 2020Review
- Heritability for stroke: Essential for taking family history.Caspian journal of internal medicine · 2020Review
- Underlying embolic and pathologic differentiation by cerebral microbleeds in cryptogenic stroke.Journal of neurology · 2020Article
- Mixed-location cerebral microbleeds as a biomarker of neurodegeneration in a memory clinic population.Aging · 2019Article
- The safety of antithrombotic therapy in patients with cerebral microbleeds and cardiogenic cerebral embolism due to nonvalvular atrial fibrillation.BMC cardiovascular disorders · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe location of cerebral microbleeds (CMBs) may differ according to ischemic stroke subtype, and the underlying pathomechanism may differ by their location. Here, we investigated the characteristics of CMBs according to various ischemic stroke subtypes to verify this issue.
methodsPatients with acute ischemic stroke were consecutively included. The presence of CMBs was determined by gradient echo image sequence. The distribution of CMBs was classified as deep, lobar, or diffuse (both deep and lobar). The prevalence, risk factors, and distribution of CMBs were compared among patients with different stroke subtypes. Factors associated with the distribution of CMBs were investigated.
resultsAmong the 1033 patients included in this study, ischemic stroke subtypes were classified as large artery atherosclerosis (LAA; n=432), small vessel occlusion (SVO; n=304), and cardioembolism (CE; n=297). The prevalence of CMBs was highest in patients with SVO (40.5%), followed by CE (33.0%) and LAA (24.8%;
conclusionsCMBs were frequently located in the lobar area in patients with CE. Previous use of antithrombotic agents is associated with lobar CMBs. The pathogenic mechanism of CMB may differ according to ischemic stroke subtype and location.
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