ArticleThe Korean journal of internal medicine2017
Impact of random urine proteinuria on maternal and fetal outcomes of pregnancy: a retrospective case-control study.
Article in The Korean journal of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 11 citations in OpenAlex.
- Predicting the Risk of Proteinuria Based on Blood Plasma Fourier-Transform Infrared Spectroscopy and Machine Learning Algorithms From Pregnant Women and Newborns.Analytical science advances · 2026Article
- Article
- The Association Between GFR Evaluated by Serum Cystatin C and Proteinuria During Pregnancy.Kidney international reports · 2019Article
- A simple pregnancy-related kidney disease screening method: random proteinuria testing.The Korean journal of internal medicine · 2017Article
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5 authors at 1 institution in 1 country.
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Abstract
BACKGROUND/
aimsProteinuria is associated with hypertension and preeclampsia in pregnancy. However, the impact of random urine proteinuria on fetal and maternal outcomes has not been established. We investigated the influence of random urine proteinuria on the clinical outcomes of pregnancy.
methodsFrom January 2008 to December 2010, 2,822 patients were retrospectively studied. A total of 536 pregnant women with proteinuria in random urine and matched controls without proteinuria via propensity score matching were analyzed. Proteinuria was checked by the dipstick method.
resultsThe patients' mean age was 33.0 ± 4.7 years, and the mean gestational age was 235.6 ± 50.6 days on admission. The prevalence of hypertension and chronic kidney disease was 2.4% (n = 67) and 1.0% (n = 29), respectively. Women with random urine proteinuria showed higher blood urea nitrogen levels and a higher incidence of hematuria. These women also had a higher incidence of preeclampsia, preterm labor, premature rupture of membranes, and intrauterine growth restriction. Proteinuria was strongly correlated with preeclampsia in both propensity score matching (p < 0.001, r = 0.783) and unmatched whole samples (p < 0.001, r = 0.851).
conclusionsThese findings suggest that random urine proteinuria is associated with preeclampsia, preterm labor, premature rupture of membrane, and intrauterine growth restriction.
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