ArticlePloS one2016
Role of the Tomato Non-Ripening Mutation in Regulating Fruit Quality Elucidated Using iTRAQ Protein Profile Analysis.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- SlSEC1- and SlSPY-mediated O-glycosylation stabilizes the transcription factor SlNOR to promote tomato fruit ripening.The Plant cell · 2026Article
- Abscisic Acid Promotes Petal Senescence in Rose by Regulating RcMYB002.Antioxidants (Basel, Switzerland) · 2026Article
- Article
- And yet another transcription factor-the complex world of fruit ripening.Plant physiology · 2024Article
- MaNAC029 modulates ethylene biosynthesis and fruit quality and undergoes MaXB3-mediated proteasomal degradation during banana ripening.Journal of advanced research · 2023Article
- Transcriptomic Analysis Reveals Genes Associated with the Regulation of Peach Fruit Softening and Senescence during Storage.Foods (Basel, Switzerland) · 2023Article
- Quantitative Transcriptomic and Proteomic Analysis of Fruit Development and Ripening in Watermelon (Frontiers in plant science · 2022Article
- Regulation of wound ethylene biosynthesis by NAC transcription factors in kiwifruit.BMC plant biology · 2021Article
- The interplay between ABA/ethylene and NAC TFs in tomato fruit ripening: a review.Plant molecular biology · 2021Review
- HEBE, a novel positive regulator of senescence in Solanum lycopersicum.Scientific reports · 2020Article
- Phytochrome-Dependent Temperature Perception Modulates Isoprenoid Metabolism.Plant physiology · 2020Article
- Re-evaluation of the nor mutation and the role of the NAC-NOR transcription factor in tomato fruit ripening.Journal of experimental botany · 2020Article
- Redox Regulation of the NOR Transcription Factor Is Involved in the Regulation of Fruit Ripening in Tomato.Plant physiology · 2020Article
- Transcriptome analysis of acerola fruit ripening: insights into ascorbate, ethylene, respiration, and softening metabolisms.Plant molecular biology · 2019Article
- Transcriptomic analysis of Citrus clementina mandarin fruits maturation reveals a MADS-box transcription factor that might be involved in the regulation of earliness.BMC plant biology · 2019Article
- New insights in the control of antioxidants accumulation in tomato by transcriptomic analyses of genotypes exhibiting contrasting levels of fruit metabolites.BMC genomics · 2019Article
- Tomato Fruit Development and Metabolism.Frontiers in plant science · 2019Review
- A NAC transcription factor, NOR-like1, is a new positive regulator of tomato fruit ripening.Horticulture research · 2018Article
- Role of the tomato TAGL1 gene in regulating fruit metabolites elucidated using RNA sequence and metabolomics analyses.PloS one · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural mutants of the Non-ripening (Nor) gene repress the normal ripening of tomato fruit. The molecular mechanism of fruit ripening regulation by the Nor gene is unclear. To elucidate how the Nor gene can affect ripening and fruit quality at the protein level, we used the fruits of Nor mutants and wild-type Ailsa Craig (AC) to perform iTRAQ (isobaric tags for relative and absolute quantitation) analysis. The Nor mutation altered tomato fruit ripening and affected quality in various respects, including ethylene biosynthesis by down-regulating the abundance of 1-aminocyclopropane-1-carboxylic acid oxidase (ACO), pigment biosynthesis by repressing phytoene synthase 1 (PSY1), ζ-carotene isomerase (Z-ISO), chalcone synthase 1 (CHS1) and other proteins, enhancing fruit firmness by increasing the abundance of cellulose synthase protein, while reducing those of polygalacturonase 2 (PG2) and pectate lyase (PL), altering biosynthesis of nutrients such as carbohydrates, amino acids, and anthocyanins. Conversely, Nor mutation also enhanced the fruit's resistance to some pathogens by up-regulating the expression of several genes associated with stress and defense. Therefore, the Nor gene is involved in the regulation of fruit ripening and quality. It is useful in the future as a means to improve fruit quality in tomato.
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