Evidence map›Paper›PMID 27732635›Full record

ArticlePloS one2016

Long-Term Prediction of the Demand of Colonoscopies Generated by a Population-Based Colorectal Cancer Screening Program.

Mercè Comas, Joan Mendivil, Montserrat Andreu, Cristina Hernández, Xavier Castells

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Simulation modeling validity and utility in colorectal cancer screening delivery: A systematic review.Journal of the American Medical Informatics Association : JAMIA · 2020
    Pooled it
  3. Risk Stratification to Optimize Colorectal Cancer Screening: Development and Validation of a Decision-Tree Model for Colonoscopy Prioritization.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
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  11. The cumulative false-positive rate in colorectal cancer screening: a Markov analysis.European journal of gastroenterology & hepatology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mercè ComasEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.ORCID http://orcid.org/0000-0003-1926-2740
Joan MendivilCPS Market Access, Roche Diagnostics International Ltd., Rotkreuz, Switzerland.
Montserrat AndreuIMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Cristina HernándezEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
Xavier CastellsEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the long-term need for colonoscopies after a positive fecal immunochemical test (FIT) and post-polypectomy surveillance in the context of a population-based colorectal cancer (CRC) screening program.

methodsA discrete-event simulation model was built to reproduce the process of CRC screening and post-polypectomy surveillance following European guidelines in a population of 100,000 men and women aged 50-69 years over a 20-year period. Screening consisted of biennial FIT and colonoscopy in participants with positive results. The model was mainly fed using data from the first and second rounds of a Spanish program (2010-2013). Data on post-polypectomy surveillance results were obtained from the literature. A probabilistic multivariate sensitivity analysis was performed on the effect of participation, FIT positivity, and adherence to surveillance colonoscopies. The main outcome variables were the number of colonoscopies after a positive FIT, surveillance colonoscopies, and the overall number of colonoscopies.

resultsAn average yearly number of 1,200 colonoscopies after a positive FIT were predicted per 100,000 inhabitants with a slight increase to 1,400 at the end of the 20-year period. Surveillance colonoscopies increased to an average of 1,000 per 100,000 inhabitants in the long-term, showing certain stabilization in the last years of the 20-year simulation horizon. The results were highly sensitive to FIT positivity.

conclusionsImplementing a population-based CRC screening program will increase the demand for colonoscopies, which is expected to double in 20 years, mainly due to an increase in surveillance colonoscopies.

Indexed as

ColonoscopyAgedColorectal NeoplasmsEarly Detection of CancerEuropeFemaleHumansMaleMass ScreeningMiddle AgedPopulation ControlProbability

Identifiers

PMID27732635
PMCPMC5061389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.