ReviewPediatric research2017
Pediatric kidney transplantation: a historical review.
Review in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05335538 (The Role of TruGraf® to Optimize Outcomes in Pediatric Renal Transplantation), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of TruGraf® to Optimize Outcomes in Pediatric Renal Transplantation
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcomes and learning curve of single-kidney transplantation from small pediatric donors in children: a retrospective cohort study with meta-analysis.Pediatric surgery international · 2026Pooled it
- Altered SIgA-targeting of gut microbiota is associated with long-term dysbiosis in pediatric solid organ transplant recipients.Gut microbes · 2026Article
- Equitable access to pediatric kidney transplantation: bridging the gap-the view from low- to lower-middle-income countries.Pediatric nephrology (Berlin, Germany) · 2026Review
- Immune monitoring by Torque Teno virus load in addition to virus-specific T cells after pediatric kidney transplantation.Clinical kidney journal · 2026Article
- Timing and Clinical Impact of Opportunistic Infections in Pediatric Kidney Transplant Recipients: A 10-Year Single-Center Experience.Journal of clinical medicine · 2026Article
- Pediatric Organ Transplantation in China.Pediatric transplantation · 2026Review
- Donor Risk Factors Affecting Graft Survival in Pediatric Kidney Transplants: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2026Article
- Implementation of a pediatric kidney transplantation program in Uzbekistan: Feasibility and early outcomes.World journal of transplantation · 2025Article
- Immunosuppressive Therapy in Pediatric Kidney Transplantation: Evolution, Current Practices, and Future Directions.Biomedicines · 2025Article
- Article
- Safety and Feasibility of Endovascular Management of Pediatric Dialysis Access.Cardiovascular and interventional radiology · 2025Article
- Adult outcomes of childhood kidney replacement therapy in Europe from 2008 to 2019: an ERA Registry study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- International validation of a pre-transplant risk assessment tool for graft survival in pediatric kidney transplant recipients.Clinical kidney journal · 2025Article
- Article
- Development of Non-HLA Antibodies and Their Association With Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Native nephrectomy in advanced pediatric kidney disease: indications, timing, and surgical approaches.Pediatric nephrology (Berlin, Germany) · 2024Review
- Pediatric kidney transplantation in Europe, a clinical snapshot pilot.Frontiers in pediatrics · 2024Article
- A pre-transplantation risk assessment tool for graft survival in Dutch pediatric kidney recipients.Clinical kidney journal · 2023Article
- Immunologic Response to SARS-CoV-2 Vaccination in Pediatric Kidney Transplant Recipients: A Systematic Review and Meta-Analysis.Vaccines · 2023Review
- The unfinished journey toward transplant equity: an analysis of racial/ethnic disparities for children after the implementation of the Kidney Allocation System in 2014.Pediatric nephrology (Berlin, Germany) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Successful renal transplantation is the optimal treatment for chronic kidney failure, but this was not always so for children. Beginning with the first kidney transplants in the 1950s, children experienced poorer patient and graft survival rates than adult patients. But over the last 6 decades, an improved understanding of the immune system which has steered pediatric multi-center clinical/pharmacokinetic and mechanistic studies that have sculpted our immunosuppression with markedly better patient and graft survivals. In addition, uniquely pediatric issues related to growth, development, neurocognitive maturation, increased complications from primary viral infections, and comorbid congenital/inherited disorders, are now diagnosed and effectively managed in these children. Refined pretransplant preparation (vaccinations for preventable diseases, attention to cognitive delays, effective dialysis and nutrition) improved donor selection, and more potent immunosuppression have all contributed to enhanced outcomes. Similarly, improvements in pediatric surgical techniques, postoperative care and better antiviral prophylaxis have all shortened hospitalizations and reduced morbidity. Today pediatric kidney transplant outcomes are markedly improved and younger children today experience better long-term graft survival than adults! While difficult problems remain, we have made tremendous progress and anticipate even more advances in the future of pediatric kidney transplantation.
Indexed as
Identifiers
27732587What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.