ArticleChildhood obesity (Print)2017
Pediatric Loss of Control Eating and High-Sensitivity C-Reactive Protein Concentrations.
Article in Childhood obesity (Print), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- A systematic review and meta-analysis of loss-of-control eating in relation to cardiometabolic health components and inflammatory markers.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Pooled it
- An evidence review of the association of immune and inflammatory markers with obesity-related eating behaviors.Frontiers in immunology · 2022Pooled it
- Remission of loss of control eating and changes in components of the metabolic syndrome.The International journal of eating disorders · 2018Trial
- A Phenome-Wide association study (PheWAS) of genetic risk for C-reactive protein in children of European Ancestry: Results from the ABCD study.Brain, behavior, and immunity · 2025Article
- Celiac Disease, Gluten-Free Diet, and Eating Disorders: From Bench to Bedside.Foods (Basel, Switzerland) · 2024Article
- A Phenome-Wide Association Study (PheWAS) of Genetic Risk for C-Reactive Protein in Children of European Ancestry: Results From the ABCD Study.medRxiv : the preprint server for health sciences · 2024Article
- Influence of puberty on relationships between body composition and blood pressure: a cross-sectional study.Pediatric research · 2023Article
- Associations between eating behaviours and cardiometabolic risk among adolescents in the Health Outcomes and Measures of the Environment study.Pediatric obesity · 2023Article
- Loss of control eating in children is associated with altered cortical and subcortical brain structure.Frontiers in psychology · 2023Article
- Article
- Heart Rate Variability and Laboratory-Based Loss-of-Control Eating in Children and Adolescents.Nutrients · 2022Article
- Dietary Risk Factors and Eating Behaviors in Peripheral Arterial Disease (PAD).International journal of molecular sciences · 2022Review
- Adolescent overeating and binge eating behavior in relation to subsequent cardiometabolic risk outcomes: a prospective cohort study.Journal of eating disorders · 2022Article
- Loss-of-Control Eating and Cardiometabolic Health in Relation to Overweight and Obesity.Current diabetes reports · 2022Review
- A comparison of negative affect and disinhibited eating between children with and without parents with type 2 diabetes.Pediatric diabetes · 2022Article
- Gut hormones, adipokines, and pro- and anti-inflammatory cytokines/markers in loss of control eating: A scoping review.Appetite · 2021Article
- Article
- Weight-based teasing in youth: Associations with metabolic and inflammatory markers.Pediatric obesity · 2021Article
- The Role of the Gut Microbiome, Immunity, and Neuroinflammation in the Pathophysiology of Eating Disorders.Nutrients · 2021Review
- Longitudinal associations between circulating interleukin-6 and C-reactive protein in childhood, and eating disorders and disordered eating in adolescence.Brain, behavior, and immunity · 2020Review
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLoss of control (LOC) eating in youth is associated with excess body weight and adiposity. After adjusting for fat mass, youth with LOC eating have higher blood pressure and higher low-density lipoprotein cholesterol compared to youth without LOC eating. Increased inflammation may account for this relationship, although few data have examined this hypothesis. Therefore, this study explored the association between LOC eating and high-sensitivity C-reactive protein (hsCRP), a marker of inflammation.
methodsWe investigated hsCRP concentrations in relation to LOC eating in a convenience sample of 194 youth (age 14.3 ± 2.1 years; 63.9% female; BMI-z 1.64 ± 1.06). The presence of LOC eating in the past month was assessed by the Eating Disorder Examination interview. Serum hsCRP was measured by enzyme-linked immunosorbent assay. Adiposity was measured by air displacement plethysmography or dual-energy x-ray absorptiometry. We compared hsCRP in those with and without LOC eating in analyses accounting for sex, adiposity, height, depressive symptoms, and eating psychopathology.
resultsYouth with LOC eating had significantly greater hsCRP than youth without LOC eating (p = 0.02), after accounting for all covariates. The number of LOC eating episodes in the past month was positively associated with hsCRP (p = 0.01). The relationship between LOC eating and hsCRP was not mediated by depressive symptoms or eating psychopathology (ps > 0.05).
conclusionsYouth with disinhibited eating may manifest increased chronic inflammation. Those with LOC eating may be an important subgroup at risk for adverse health outcomes associated with both chronic inflammation and obesity. Future research should examine whether hsCRP concentrations mediate the relationship between LOC eating and its association with cardiometabolic risk.
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Registered trials
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