Evidence map›Paper›PMID 27731980›Full record

ArticleBiochemistry2016

Sarcolipin Promotes Uncoupling of the SERCA Ca

Joseph M Autry, David D Thomas, L Michel Espinoza-Fonseca

Abstract read
In one paragraph

Article in Biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Multistate Kinetic Model of the Sodium-Potassium ATPase.The journal of physical chemistry. B · 2025
    Article
  6. SERCA blockade as a treatment strategy for obesity.European journal of applied physiology · 2025
    Review
  7. Article
  8. Article
  9. Replacement of Lys27 by asparagine in the SERCA regulator myoregulin: A CaBiochimica et biophysica acta. Molecular cell research · 2024
    Review
  10. Isolation of the Sarcoplasmic Reticulum CaMethods and protocols · 2023
    Article
  11. A general overview of the multifactorial adaptation to cold: biochemical mechanisms and strategies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joseph M AutryDepartment of Biochemistry, Molecular Biology, and Biophysics and ‡Biophysical Technology Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.
David D ThomasDepartment of Biochemistry, Molecular Biology, and Biophysics and ‡Biophysical Technology Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.
L Michel Espinoza-FonsecaDepartment of Biochemistry, Molecular Biology, and Biophysics and ‡Biophysical Technology Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.
University of Minnesota · US

Funding

Structural Dynamics of Muscle Calcium ATPase RegulationR01GM027906 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI THOMAS, DAVID D · 1985 to 2016
$8.6M
Molecular mechanisms and regulation of the calcium pump in the heartR01GM120142 · NIGMS · UNIVERSITY OF MINNESOTA · PI ESPINOZA-FONSECA, LENNANE MICHEL · 2016 to 2020
$1.7M
American Heart Association-American Stroke Association 12SDG12060656NIGMS NIH HHS R01 GM027906NIGMS NIH HHS R01 GM120142
6 · The paper itself

Abstract

We have performed microsecond (μs) molecular dynamics simulation (MDS) to identify structural mechanisms for sarcolipin (SLN) uncoupling of Ca

Indexed as

Energy MetabolismSignal TransductionMuscle ProteinsProtein ConformationProteolipidsSarcoplasmic Reticulum Calcium-Transporting ATPasesMuscle ProteinsProteolipidssarcolipinSarcoplasmic Reticulum Calcium-Transporting ATPases

Identifiers

PMID27731980
PMCPMC5506494
OpenAlexW2531568775

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.