Evidence map›Paper›PMID 27731894›Full record

ArticleHeadache2016

Patterns of Use of Peripheral Nerve Blocks and Trigger Point Injections for Pediatric Headache: Results of a Survey of the American Headache Society Pediatric and Adolescent Section.

Christina L Szperka, Amy A Gelfand, Andrew D Hershey

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Headache, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03526874 (Occipital Nerve Blocks for Acute Treatment of Pediatric Migraine), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03526874 phase3completednot on this mapstarted 2019, after this paper: background citation

Occipital Nerve Blocks for Acute Treatment of Pediatric Migraine

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2019 to 2023Enrolled63ConditionsChronic Migraine, Headache, Episodic MigraineArmsLidocaine 4% Topical Application Cream [LMX 4], Lidocaine Hydrochloride 2 mg/mL Injectable Solution, Normal Saline
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Update of New Daily Persistent Headache.Current pain and headache reports · 2022
    Review
  8. Article
  9. Article
  10. Approach to Pediatric Intractable Migraine.Current neurology and neuroscience reports · 2021
    Review
  11. Peripheral Occipital Nerve Decompression Surgery in Migraine Headache.Plastic and reconstructive surgery. Global open · 2020
    Article
  12. Review
  13. ED and Inpatient Management of Headache in Children and Adolescents.Current neurology and neuroscience reports · 2020
    Review
  14. Review
  15. Article
  16. Nerve Blocks in Pediatric and Adolescent Headache Disorders.Current pain and headache reports · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Christina L SzperkaDepartment of Neurology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Amy A GelfandDepartments of Neurology and Pediatrics, University of California San Francisco (UCSF), San Francisco, CA, USA.
Andrew D HersheyDepartment of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center · USUniversity of California, San Francisco · USUniversity of Pennsylvania · US

Funding

Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
Amitriptyline and Topiramate in the Prevention of Childhood MigraineU01NS076788 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI HERSHEY, ANDREW D, POWERS, SCOTT W · 2011 to 2014
$9.3M
Neurologic Clinical Epidemiology Training ProgramT32NS061779 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider, Allison Willis · 2008 to 2026
$4.6M
NCATS NIH HHS KL2 TR000143NCATS NIH HHS KL2 TR001870NINDS NIH HHS T32 NS061779NINDS NIH HHS U01 NS076788
6 · The paper itself

Abstract

objectiveTo describe current patterns of use of nerve blocks and trigger point injections for treatment of pediatric headache.

backgroundPeripheral nerve blocks are often used to treat headaches in adults and children, but the available studies and practice data from adult headache specialists have shown wide variability in diagnostic indications, sites injected, and medication(s) used. The purpose of this study was to describe current practice patterns in the use of nerve blocks and trigger point injections for pediatric headache disorders.

methodsA survey was created in REDCap, and sent via email to the 82 members of the Pediatric and Adolescent Section of the American Headache Society in June 2015. The survey queried about current practice and use of nerve blocks, as well as respondents' opinions regarding gaps in the evidence for use of nerve blocks in this patient population.

resultsForty-one complete, five incomplete, and three duplicate responses were submitted (response rate complete 50%). About 78% of the respondents identified their primary specialty as Child Neurology, and 51% were certified in headache medicine. Twenty-six (63%) respondents perform nerve blocks themselves, and seven (17%) refer patients to another provider for nerve blocks. Chronic migraine with status migrainosus was the most common indication for nerve blocks (82%), though occipital neuralgia (79%), status migrainosus (73%), chronic migraine without flare (70%), post-traumatic headache (70%), and new daily persistent headache (67%) were also common indications. The most commonly selected clinically meaningful response for status migrainosus was ≥50% reduction in severity, while for chronic migraine this was a ≥50% decrease in frequency at 4 weeks. Respondents inject the following locations: 100% inject the greater occipital nerve, 69% lesser occipital nerve, 50% supraorbital, 46% trigger point injections, 42% auriculotemporal, and 34% supratrochlear. All respondents used local anesthetic, while 12 (46%) also use corticosteroid (8 bupivacaine only, 4 each lidocaine + bupivacaine, lidocaine + corticosteroid, bupivacaine + corticosteroid, lidocaine + bupivacaine + corticosteroid, and 2 lidocaine only).

conclusionDespite limited evidence, nerve blocks are commonly used by pediatric headache specialists. There is considerable variability among clinicians as to injection site(s) and medication selection, indicating a substantial gap in the literature to guide practice, and supporting the need for further research in this area.

Indexed as

Trigger PointsAdolescentAnesthetics, LocalChildChild, PreschoolFemaleHeadacheHealth SurveysHumansInjectionsMaleNerve BlockPediatricsSocieties, MedicalSurveys and QuestionnairesTime FactorsAnesthetics, Localheadachemigrainepediatricperipheral nerve blockpractice survey

Identifiers

PMID27731894
PMCPMC5830113
OpenAlexW2531341904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.