Evidence map›Paper›PMID 27731867›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2016

MiR-940 Inhibited Cell Growth and Migration in Triple-Negative Breast Cancer.

Lingmi Hou, Maoshan Chen, Hongwei Yang, Tianyong Xing, Jingdong Li, Guangwu Li, Lina Zhang, Shishan Deng, Jiani Hu, Xiaobo Zhao and 1 more

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. JHDM1D-AS1-driven inhibition of miR-940 releases ARTN expression to induce breast carcinogenesis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
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  9. Suppression of circulatingOncology letters · 2021
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lingmi HouDepartment of Thyroid Breast Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China (mainland).
Maoshan ChenDepartment of Breast and Thyroid Surgery, Suining Central Hospital, Suining, Sichuan, China (mainland).
Hongwei YangDepartment of Breast and Thyroid Surgery, Suining Central Hospital, Suining, Sichuan, China (mainland).
Tianyong XingDepartment of Thyroid Breast Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China (mainland).
Jingdong LiInstitute of Hepatobiliarypancreatic-Intestinal Diseases, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China (mainland).
Guangwu LiDepartment of Radiology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China (mainland).
Lina ZhangDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China (mainland).
Shishan DengDepartment of Anatomy, The North Sichuan Medical College, Nanchong, Sichuan, China (mainland).
Jiani HuDepartment of Radiology, Wayne State University, Detroit, MI, USA.
Xiaobo ZhaoDepartment of Thyroid Breast Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China (mainland).
Jun JiangBreast Disease Center, Southwest Hospital, Third Military Medical University, Chongqing, China (mainland).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Breast cancer is the main type of cancer in women, and triple-negative breast cancer (TNBC) is a unique subtype of breast cancer. The expression of miR-940 has been shown to play an important role in various cancers; however, the role of miR-940 in TNBC remains unknown. MATERIAL AND METHODS The expression of miR-940 in TNBC tissues or cells were tested by qRT-PCR; the expression of miR-940 in cells were overexpressed by miR-940 mimics, and suppressed by anti-miR-940. Bioinformatics algorithms from TargetScanHuman were used to predict the target genes of miR-940. The interaction between miR-940 and ZNF24 was confirmed by dual luciferase assays. The protein level was assayed by Western blot. RESULTS TNBC tissues and cells showed lower miR-940 levels. CONCLUSIONS MiR-940 inhibited cellular proliferation and migration in TNBC.

Indexed as

Cell Line, TumorCell MovementCell ProliferationCells, CulturedFemaleGene Expression Regulation, NeoplasticHumansKruppel-Like Transcription FactorsMicroRNAsPrognosisTriple Negative Breast NeoplasmsKruppel-Like Transcription FactorsMicroRNAsMIRN940 microRNA, humanZNF24 protein, human

Identifiers

PMID27731867
PMCPMC5072378

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.