ArticleScientific reports2016
Identification, Distribution and Population Dynamics of Francisella-like Endosymbiont in Haemaphysalis doenitzi (Acari: Ixodidae).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 25 citations in OpenAlex.
- Country-wide assessment of tick-borne pathogens collected in ticks between 2021 and 2024 in Germany, with a focus onOne health (Amsterdam, Netherlands) · 2025Article
- Genetic and genomic variability ofISME communications · 2025Article
- Novel Francisella-like endosymbiont and Anaplasma species from Amblyomma nodosum hosted by the anteater Tamandua Mexicana in Mexico.Experimental & applied acarology · 2023Article
- Impact of endosymbionts on tick physiology and fitness.Parasitology · 2023Review
- Ecological Contacts and Host Specificity Promote Replacement of Nutritional Endosymbionts in Ticks.Microbial ecology · 2022Article
- What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022Review
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- Recent advances in understanding tick and rickettsiae interactions.Parasite immunology · 2021Review
- Reorganized Genomic Taxonomy ofMicroorganisms · 2021Article
- Ticks and Tularemia: Do We Know What We Don't Know?Frontiers in cellular and infection microbiology · 2019Review
- Article
- Symbiont dynamics of the Tibetan tick Haemaphysalis tibetensis (Acari: Ixodidae).Parasites & vectors · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Francisella-like endosymbionts (FLEs) with significant homology to Francisella tularensis (γ-proteobacteria) have been characterized in several tick species, whereas knowledge on their distribution and population dynamics in ticks remains meager. Hence, in the current study, we identified a novel Francisella-like endosymbiont (FLEs-Hd) from the tick Haemaphysalis doenitzi and evaluated the putative functions of this symbiont. Results indicated that FLEs-Hd had 100% infection rate and a perfect vertical transmission in H. doenitzi, and that it is distributed in ovaries, malpighian tubules, salivary glands and midguts of the ticks, suggesting that FLEs-Hd presumably is a crucial symbiont of the host without specific tissue tropism. To further explore the function of the symbiont, the population dynamics of FLEs-Hd at each developmental stage of ticks and in tissues at different reproductive statuses were determined by real-time quantitative polymerase chain reaction (real-time qPCR). Results showed that the high density and regular population dynamics of FLEs-Hd appeared in female ovaries, suggesting that the symbiont may provide necessary nutrients or regulators to ensure normal ovary development of ticks.
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