ArticleAnnals of surgical oncology2017
Impact of Neoadjuvant Chemotherapy on Clinical Risk Scores and Survival in Patients with Colorectal Liver Metastases.
Article in Annals of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Missing colorectal liver metastases: the surgical challenge.Langenbeck's archives of surgery · 2021Pooled it
- Artificial intelligence-driven body composition analysis and its association with survival in patients with colorectal liver metastases.Contemporary oncology (Poznan, Poland) · 2026Article
- Total Metastases Volume and Relative Volume Reduction After Neoadjuvant Therapy Predict Outcome After Liver Resection of Colorectal Liver Metastases.Annals of surgical oncology · 2025Article
- Current landscape of preoperative neoadjuvant therapies for initial resectable colorectal cancer liver metastasis.World journal of gastroenterology · 2024Review
- Local interventions for colorectal cancer metastases to liver and lung.Irish journal of medical science · 2023Article
- Predictive Factors for the Survival Outcomes of Preoperative Chemotherapy in Patients with Resectable and Borderline Resectable Colorectal Cancer with Liver Metastasis.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Review
- Composite Score: prognostic tool to predict survival in patients undergoing surgery for colorectal liver metastases.BJS open · 2021Article
- Risk scoring system for recurrence after simultaneous resection of colorectal cancer liver metastasis.Annals of translational medicine · 2021Article
- Hepatic resection after neoadjuvant chemotherapy for patients with liver metastases from colorectal cancer: need for cautious planning.Annals of surgical treatment and research · 2019Article
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Authors and funding
7 authors.
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Abstract
backgroundSeveral clinical risk scores for patients with colorectal liver metastases (CLM) were established in cohorts of patients undergoing liver resection (LR) without neoadjuvant chemotherapy (NAC). The purpose of the study was to evaluate the predictive values of four common risk scores in the setting of NAC and the impact of score changes during NAC.
methodsRisk scores (Fong, Nordlinger, Nagashima, and Konopke) were retrospectively calculated for 336 patients undergoing LR for CLM, including 109 patients without and 227 patients with NAC. In patients with NAC, the scores were calculated before and after NAC.
resultsIn patients without NAC (n = 109), all risk scores except the Konopke score showed a significant correlation with disease-free survival (DFS). Only the Nagashima score also was predictive for overall survival (OS). In patients with NAC (n = 227), all scores except the Konopke score were predictive for DFS and OS before and after NAC. Score changes in the Fong and the Nagashima score showed a significant correlation with DFS and OS.
conclusionsNagashima score was the most universally applicable score and predicted prognosis in all tested scenarios.
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