Evidence map›Paper›PMID 27730152›Full record

ArticleERJ open research2015

VAC chemotherapy with valproic acid for refractory/relapsing small cell lung cancer: a phase II study.

Thierry Berghmans, Jean-Jacques Lafitte, Arnaud Scherpereel, Lieveke Ameye, Marianne Paesmans, Anne-Pascale Meert, Benoit Colinet, Christian Tulippe, Luc Willems, Nathalie Leclercq and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Metal Ion Signaling in Biomedicine.Chemical reviews · 2025
    Review
  2. Sodium homeostasis in the tumour microenvironment.Biochimica et biophysica acta. Reviews on cancer · 2019
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Thierry BerghmansDepartment of Intensive Care Unit and Thoracic Oncology, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles (ULB), Brussels, Belgium.
Jean-Jacques LafitteDepartment of Pulmonary and Thoracic Oncology, CHRU de Lille and University of Lille II, France.
Arnaud ScherpereelDepartment of Pulmonary and Thoracic Oncology, CHRU de Lille and University of Lille II, France.
Lieveke AmeyeData Centre, Institut Jules Bordet, Centre des Tumeurs de l'ULB, Brussels, Belgium.
Marianne PaesmansData Centre, Institut Jules Bordet, Centre des Tumeurs de l'ULB, Brussels, Belgium.
Anne-Pascale MeertDepartment of Intensive Care Unit and Thoracic Oncology, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles (ULB), Brussels, Belgium.
Benoit ColinetDepartment of Pneumology, Grand Hôpital de Charleroi, Gilly, Belgium.
Christian TulippeDepartment of Pneumology, CH Mouscron, Mouscron, Belgium.
Luc WillemsGembloux Agro-Bio Tech and Interdisciplinary Cluster for Applied Genoproteomics (GIGA), University of Liège, Gembloux, Belgium.
Nathalie LeclercqDepartment of Intensive Care Unit and Thoracic Oncology, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles (ULB), Brussels, Belgium.
Jean-Paul SculierDepartment of Intensive Care Unit and Thoracic Oncology, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles (ULB), Brussels, Belgium.
European Lung Cancer Working Party
Institut Jules Bordet · BECentre Hospitalier Universitaire de Lille · FRUniversité Libre de Bruxelles · BECentre Hospitalier de Mouscron · BEGembloux Agro-Bio Tech · BEGrand Charleroi Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salvage chemotherapy (CT) for relapsing or refractory small cell lung cancer (SCLC) remains disappointing.

Identifiers

PMID27730152
PMCPMC5005117
OpenAlexW2269171823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.