Evidence map›Paper›PMID 27729515›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Cis-eQTLs regulate reduced LST1 gene and NCR3 gene expression and contribute to increased autoimmune disease risk.

Guiyou Liu, Yang Hu, Shuilin Jin, Fang Zhang, Qinghua Jiang, Junwei Hao

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Disease status affects the association between rs4813620 and the expression of Alzheimer's disease susceptibility geneProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Autoimmune disease variants regulateProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  15. Article
  16. Rs4878104 contributes to Alzheimer's disease risk and regulates DAPK1 gene expression.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Guiyou LiuSchool of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Yang HuSchool of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Shuilin JinDepartment of Mathematics, Harbin Institute of Technology, Harbin 150001, China.
Fang ZhangDepartment of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Qinghua JiangSchool of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China; hjw@tmu.edu.cn qhjiang@hit.edu.cn.
Junwei HaoDepartment of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China hjw@tmu.edu.cn qhjiang@hit.edu.cn.
Harbin Institute of Technology · CNTianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genome-Wide Association StudyQuantitative Trait LociAutoimmune DiseasesGene ExpressionGene Expression RegulationHumansPolymorphism, Single Nucleotide

Identifiers

PMID27729515
PMCPMC5081638
OpenAlexW2531017381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.