Evidence map›Paper›PMID 27729363›Full record

ArticleCirculation. Cardiovascular imaging2016

A Magnetic Resonance Imaging-Conditional External Cardiac Defibrillator for Resuscitation Within the Magnetic Resonance Imaging Scanner Bore.

Ehud J Schmidt, Ronald D Watkins, Menekhem M Zviman, Michael A Guttman, Wei Wang, Henry A Halperin

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Interventional cardiovascular magnetic resonance: state-of-the-art.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Evaluation of a real-time magnetic resonance imaging-guided electrophysiology system for structural and electrophysiological ventricular tachycardia substrate assessment.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2019
    Article
  9. High-energy external defibrillation and transcutaneous pacing during MRI: feasibility and safety.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  10. Advances in Real-Time MRI-Guided Electrophysiology.Current cardiovascular imaging reports · 2019
    Article
  11. Magnetic resonance imaging guidance for the optimization of ventricular tachycardia ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2018
    Review
  12. Right heart catheterization using metallic guidewires and low SAR cardiovascular magnetic resonance fluoroscopy at 1.5 Tesla: first in human experience.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Article
  13. Real-time MRI guidance of cardiac interventions.Journal of magnetic resonance imaging : JMRI · 2017
    Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ehud J SchmidtFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.). eschmidt3@partners.org.
Ronald D WatkinsFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.).
Menekhem M ZvimanFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.).
Michael A GuttmanFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.).
Wei WangFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.).
Henry A HalperinFrom the Department of Radiology, Brigham and Women's Hospital, Boston, MA (E.J.S., W.W.); Department of Radiology, Stanford University, CA (R.D.W.); and Department of Cardiology, Johns Hopkins University, Baltimore, MD (M.M.Z., M.A.G., H.A.H.).
Stanford University · USBrigham and Women's Hospital · US

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
Boston Biomedical Innovation CenterU54HL119145 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLAN, DAVID E., LOSCALZO, JOSEPH · 2013 to 2021
$18.8M
ULTRASOUND THERAPY DELIVERY THROUGH INTACT SKULLU41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLBY, ALEXANDRA J · 2005 to 2009
$17.2M
Improved Targeting and Assessment of Electrophysiology InterventionR01HL094610 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HALPERIN, HENRY R · 2009 to 2018
$15.5M
Improved arrhythmia imaging with MR compatible 12-lead ECGR03EB013873 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHMIDT, EHUD JERUHAM · 2012 to 2013
$170k
NCRR NIH HHS U41 RR019703NHLBI NIH HHS R01 HL094610NHLBI NIH HHS U54 HL119145NIBIB NIH HHS P41 EB015898NIBIB NIH HHS R03 EB013873
6 · The paper itself

Abstract

backgroundSubjects undergoing cardiac arrest within a magnetic resonance imaging (MRI) scanner are currently removed from the bore and then from the MRI suite, before the delivery of cardiopulmonary resuscitation and defibrillation, potentially increasing the risk of mortality. This precludes many higher-risk (acute ischemic and acute stroke) patients from undergoing MRI and MRI-guided intervention. An MRI-conditional cardiac defibrillator should enable scanning with defibrillation pads attached and the generator ON, enabling application of defibrillation within the seconds of MRI after a cardiac event. An MRI-conditional external defibrillator may improve patient acceptance for MRI procedures. METHODS AND

resultsA commercial external defibrillator was rendered 1.5 Tesla MRI-conditional by the addition of novel radiofrequency filters between the generator and commercial disposable surface pads. The radiofrequency filters reduced emission into the MRI scanner and prevented cable/surface pad heating during imaging, while preserving all the defibrillator monitoring and delivery functions. Human volunteers were imaged using high specific absorption rate sequences to validate MRI image quality and lack of heating. Swine were electrically fibrillated (n=4) and thereafter defibrillated both outside and inside the MRI bore. MRI image quality was reduced by 0.8 or 1.6 dB, with the generator in monitoring mode and operating on battery or AC power, respectively. Commercial surface pads did not create artifacts deeper than 6 mm below the skin surface. Radiofrequency heating was within US Food and Drug Administration guidelines. Defibrillation was completely successful inside and outside the MRI bore.

conclusionsA prototype MRI-conditional defibrillation system successfully defibrillated in the MRI without degrading the image quality or increasing the time needed for defibrillation. It can increase patient acceptance for MRI procedures.

Indexed as

DefibrillatorsTime-to-TreatmentAnimalsDisease Models, AnimalElectric CountershockEquipment DesignHeart ArrestHumansMagnetic Resonance ImagingMaterials TestingResuscitationSus scrofaartifactscardiopulmonary resuscitationdefibrillatorsmagnetic resonance imagingstroke

Identifiers

PMID27729363
PMCPMC5079441
OpenAlexW2531359388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.