Evidence map›Paper›PMID 27729277›Full record

ReviewNeuroImage2017

Is the statistic value all we should care about in neuroimaging?

Gang Chen, Paul A Taylor, Robert W Cox

Abstract readReview
In one paragraph

Review in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Trial
  6. Ultradian rhythmicity of plasma cortisol is necessary for normal emotional and cognitive responses in man.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Trial
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gang ChenScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA. Electronic address: gangchen@mail.nih.gov.
Paul A TaylorScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA.
Robert W CoxScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA.

Funding

Scientific and Statistical Computing CoreZICMH002888 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI TAYLOR, PAUL · 2009 to 2025
$30.9M
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIC MH002888
6 · The paper itself

Abstract

Here we address an important issue that has been embedded within the neuroimaging community for a long time: the absence of effect estimates in results reporting in the literature. The statistic value itself, as a dimensionless measure, does not provide information on the biophysical interpretation of a study, and it certainly does not represent the whole picture of a study. Unfortunately, in contrast to standard practice in most scientific fields, effect (or amplitude) estimates are usually not provided in most results reporting in the current neuroimaging publications and presentations. Possible reasons underlying this general trend include (1) lack of general awareness, (2) software limitations, (3) inaccurate estimation of the BOLD response, and (4) poor modeling due to our relatively limited understanding of FMRI signal components. However, as we discuss here, such reporting damages the reliability and interpretability of the scientific findings themselves, and there is in fact no overwhelming reason for such a practice to persist. In order to promote meaningful interpretation, cross validation, reproducibility, meta and power analyses in neuroimaging, we strongly suggest that, as part of good scientific practice, effect estimates should be reported together with their corresponding statistic values. We provide several easily adaptable recommendations for facilitating this process.

Indexed as

Data Interpretation, StatisticalReproducibility of ResultsFunctional NeuroimagingHumans

Identifiers

PMID27729277
PMCPMC6591724

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.