Evidence map›Paper›PMID 27729276›Full record

ArticleNeuroImage2017

Rapid simultaneous high-resolution mapping of myelin water fraction and relaxation times in human brain using BMC-mcDESPOT.

Mustapha Bouhrara, Richard G Spencer

Open access · greenAbstract read
In one paragraph

Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Evidence of association between higher cardiorespiratory fitness and higher cerebral myelination in aging.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. The Effect of the Human Brainstem Myelination on Gait Speed in Normative Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  20. REUSED: A deep neural network method for rapid whole-brain high-resolution myelin water fraction mapping from extremely under-sampled MRI.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mustapha BouhraraMagnetic Resonance Imaging and Spectroscopy Section, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Intramural Research Program, BRC 04B-116, 251 Bayview Boulevard, Baltimore, MD 21224, USA. Electronic address: bouhraram@mail.nih.gov.
Richard G SpencerMagnetic Resonance Imaging and Spectroscopy Section, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Intramural Research Program, BRC 04B-116, 251 Bayview Boulevard, Baltimore, MD 21224, USA. Electronic address: spencer@helix.nih.gov.
Institute on Aging · USNational Institutes of Health · US

Funding

Advanced magnetic resonance imaging of the human brain in normative aging, cognitive impairment, and dementiaZIAAG000452 · NIA · NATIONAL INSTITUTE ON AGING · PI SPENCER, RICHARD · 2017 to 2025
$1.4M
Intramural NIH HHS Z99 AG999999
6 · The paper itself

Abstract

A number of central nervous system (CNS) diseases exhibit changes in myelin content and magnetic resonance longitudinal, T

Indexed as

Myelin SheathAdultBayes TheoremBody WaterBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMonte Carlo MethodYoung AdultBrainHigh-resolution mappingMRIMyelin water fractionRelaxation times

Identifiers

PMID27729276
PMCPMC5303643
OpenAlexW2530170980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.