Evidence map›Paper›PMID 27729081›Full record

ReviewGlobalization and health2016

Eradicating polio in Pakistan: an analysis of the challenges and solutions to this security and health issue.

Shoaib Fahad Hussain, Peter Boyle, Preeti Patel, Richard Sullivan

Registry-linked trialAbstract readReview
In one paragraph

Review in Globalization and health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04432935 (Effect of Bovine Lactoferrin on Seroconversion Following Polio Vaccine Administration in Children), which is not on this map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04432935 nacompletednot on this mapstarted 2020, after this paper: background citation

Effect of Bovine Lactoferrin on Seroconversion Following Polio Vaccine Administration in Children: A Randomized Control Trial

TypeinterventionalSponsorAga Khan UniversityRan2020 to 2022Enrolled468ConditionsPoliomyelitisArmsBovine Lactoferrin, Placebo Glucon D
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shoaib Fahad HussainConflict and Health Research Group, King's Centre for Global Health, King's College London, Suite 2.13 Weston Education Centre, Cutcombe Road, London, SE5 9RJ, UK. shoaib_fahad.hussain@kcl.ac.uk.ORCID 0000-0003-3551-3781
Peter BoyleInternational Prevention Research Institute, Lyon, France.
Preeti PatelDepartment of War Studies and Conflict and Health Research Group, King's College London, London, UK.
Richard SullivanConflict and Health Research Group, King's Centre for Global Health, King's College London, Suite 2.13 Weston Education Centre, Cutcombe Road, London, SE5 9RJ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988 the global incidence of poliomyelitis has fallen by nearly 99 %. From a situation where wild type poliovirus was endemic in 125 countries across five continents, transmission is now limited to regions of just three countries - Pakistan, Afghanistan and Nigeria. A sharp increase in Pakistan's poliomyelitis cases in 2014 prompted the International Health Regulations Emergency Committee to declare the situation a 'public health emergency of international concern'. Global polio eradication hinges on Pakistan's ability to address the religious, political and socioeconomic barriers to immunisation; including discrepancies in vaccine coverage, a poor health infrastructure, and conflict in polio-endemic regions of the country. This analysis provides an overview of the GPEI, focusing on the historical and contemporary challenges facing Pakistan's polio eradication programme and the impact of conflict and insecurity, and sheds light on strategies to combat vaccine hesitancy, engage local communities and build on recent progress towards polio eradication in Pakistan.

Indexed as

Disease EradicationHumansOrganization and AdministrationPakistanPoliomyelitisPublic HealthSecurity MeasuresSocial ClassVaccinationWarfareWorkforceConflict and healthGlobal healthPakistanPolioSocioeconomic factorsVaccine coverage

Identifiers

PMID27729081
PMCPMC5059991

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.