Evidence map›Paper›PMID 27729031›Full record

ReviewBMC infectious diseases2016

Meningitis in a Chinese adult patient caused by Mycoplasma hominis: a rare infection and literature review.

Menglan Zhou, Peng Wang, Sharon Chen, Bin Du, Jinlong Du, Fengdan Wang, Meng Xiao, Fanrong Kong, Yingchun Xu

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Central nervous system infection caused by Mycoplasma hominis in an adult: a case report and literature review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Postoperative meningitis in pediatric posterior fossa tumors: risk stratification and the role of early CSF cytology.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. BMJ case reports · 2023
    Article
  9. Soft-tissue infection due to Mycoplasma hominis.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Article
  10. Case Report: Double trouble: a rare case of successfully treatedFrontiers in cellular and infection microbiology · 2023
    Article
  11. World journal of clinical cases · 2022
    Article
  12. Diagnosis ofInfection and drug resistance · 2022
    Article
  13. A Case Report ofFrontiers in medicine · 2022
    Article
  14. Lipoic Acid Does Not Affect The Growth ofPolish journal of microbiology · 2021
    Article
  15. [Clinical implications of the genus Mycoplasma].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  16. IntracranialIDCases · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Menglan ZhouDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.ORCID 0000-0003-1241-6153
Peng WangDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
Sharon ChenCentre for Infectious Diseases and Microbiology Laboratory Services, Pathology West, Westmead Hospital, University of Sydney Darcy Road, Westmead, New South Wales, 2145, Australia.
Bin DuDepartment of Medical Intensive Care Unit, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Jinlong DuDepartment of Clinical Laboratory, Fu Xing Hospital, Capital Medical University, Beijing, China.
Fengdan WangDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Meng XiaoDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
Fanrong KongCentre for Infectious Diseases and Microbiology Laboratory Services, Pathology West, Westmead Hospital, University of Sydney Darcy Road, Westmead, New South Wales, 2145, Australia.
Yingchun XuDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China. xycpumch@139.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNThe University of Sydney · AUCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycoplasma hominis, a well known cause of neonatal infection, has been reported as a pathogen in urogenital infections in adults; however, central nervous system (CNS) infections are rare. We report here the first case of M. hominis meningitis in China, post neurosurgical treatment for an intracerebral haemorrhage in a 71-year-old male. CASE PRESENTATION: We describe a 71-year-old man who developed M. hominis meningitis after neurosurgical treatment and was successfully treated with combined azithromycin and minocycline therapy of 2 weeks duration, despite delayed treatment because the Gram stain of cerebrospinal fluid (CSF) yielded no visible organisms. The diagnosis required 16S rDNA sequencing analysis of the cultured isolate from CSF. Literature review of M. hominis CNS infections yielded 19 cases (13 instances of brain abscess, 3 of meningitis, 1 spinal cord abscess and 1 subdural empyema each). Delay in diagnosis and initial treatment failure was evident in all cases. With appropriate microbiological testing, antibiotic therapy (ranging from 5 days to 12 weeks) and often, multiple surgical interventions, almost all the patients improved immediately.

conclusionsBoth our patient findings and the literature review, highlighted the pathogenic potential of M. hominis together with the challenges prompted by rare infectious diseases in particular for developing countries laboratories with limited diagnostic resources.

Indexed as

AgedAnti-Bacterial AgentsAsian PeopleHumansMaleMeningitis, BacterialMycoplasma hominisMycoplasma InfectionsTreatment FailureAnti-Bacterial AgentsCase reportHospital acquired pneumoniaMeningitisMycoplasma hominisPost-operative infection

Identifiers

PMID27729031
PMCPMC5059901
OpenAlexW2531203101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.