Evidence map›Paper›PMID 27729024›Full record

ReviewBMC pregnancy and childbirth2016

Why non-invasive maternal hemodynamics assessment is clinically relevant in early pregnancy: a literature review.

Sharona Vonck, Anneleen Simone Staelens, Ine Bollen, Lien Broekx, Wilfried Gyselaers

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in BMC pregnancy and childbirth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04801121 (Fetal Growth and Placental Function in Pregnancies Complicated by Diabetes), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04801121 unknown statusnot on this mapstarted 2020, after this paper: background citation

Fetal Growth and Placental Function in Pregnancies Complicated by Diabetes

Typeobservational_patient_registrySponsorSidsel Linneberg RathckeRan2020 to 2023Enrolled100ConditionsPregnancy in Diabetics, Placenta, Fetal Growth, Magnetic Resonance Imaging
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. ISUOG Consensus Statement on maternal hemodynamic assessment in hypertensive disorders of pregnancy and fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sharona VonckFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium. sharona.vonck@zol.be.
Anneleen Simone StaelensFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Ine BollenFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Lien BroekxFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Wilfried GyselaersFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Hasselt University · BEZiekenhuis Oost-Limburg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe maternal cardiovascular system adapts quickly when embryo implantation is recognized by the body. Those adaptations play an important role, as a normal cardiovascular adaptation is a requirement for a normal course of pregnancy. Disturbed adaptations predispose to potential hypertensive disorders further in pregnancy [1-3]. This report aims to briefly inform the obstetricians, general practitioners and midwives, who are the key players in detecting and treating hypertensive disorders during pregnancy.

methodsThe PubMed database was used as main tool to find studies involving clearly defined first trimester hemodynamic changes in normal pregnancies and hypertensive pregnancies. In addition, the bibliographies of these studies were investigated for further relevant literature.

resultsA comprehensive overview is given concerning the normal adaptations in the cardiovascular tree in a first trimester pregnancy. Additionally, signs of abnormal cardiovascular changes observed in first trimester are described together with the normal reference range for each non-invasive, easily applicable technique for maternal hemodynamics assessment.

conclusionsWith a combination of techniques, it is possible to integrate and evaluate the maternal heart, veins and arteries at 12 weeks of pregnancy. Applying those techniques into the daily clinic opens perspectives to prevention and prophylactic treatment, aiming for a reduction of the risk for hypertension during pregnancy.

Indexed as

Adaptation, PhysiologicalFemaleHemodynamicsHumansPregnancyPregnancy Trimester, FirstPrenatal DiagnosisEarly pregnancyFirst trimesterHypertensionMaternal hemodynamicsReference values

Identifiers

PMID27729024
PMCPMC5059982
OpenAlexW2530913511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.