The Supplement Paradox: Negligible Benefits, Robust Consumption.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. A randomized control trial of high-dose micronutrient-antioxidant supplementation in healthy persons with untreated HIV infection.PloS one · 2022
   Trial
2. The effects of omega-3 fatty acids on neuropsychological functioning and brain morphology in mid-life adults: a randomized clinical trial.Psychological medicine · 2020
   Trial
3. Consumer Preference and Willingness to Pay for Nutraceuticals to Prevent Cardiovascular Diseases in Thailand: A Discrete Choice Experiment.Nutrients · 2026
   Article
4. Vitamin D-Related Information Exposure, Attitudes, and Practices Among Prostate and Breast Cancer Survivors in Poland: Implications for Patient-Physician Communication.Nutrients · 2026
   Article
5. Exploring motivations, information behavior, perceptions, and intentions among dietary supplement users: a cross-sectional survey study in Germany.Frontiers in nutrition · 2025
   Article
6. Exploring GP and patient attitudes towards the use and deprescribing of dietary supplements: a survey study in Switzerland.BMC primary care · 2024
   Article
7. Determinants of Knowledge About Dietary Supplements Among Polish Internet Users: Nationwide Cross-sectional Study.Journal of medical Internet research · 2021
   Article
8. Is there a role for botanical medicines in the twenty-first century?: Promotion of untested traditional therapies by the World Health Organization and China endangers global public health.EMBO reports · 2020
   Article
9. Alternative therapies in academic medical centers compromise evidence-based patient care.The Journal of clinical investigation · 2020
   Review
10. Critical Differences Between Dietary Supplement and Prescription Omega-3 Fatty Acids: A Narrative Review.Advances in therapy · 2020
    Review
11. Knowledge about dietary supplements and trust in advertising them: Development and validation of the questionnaires and preliminary results of the association between the constructs.PloS one · 2019
    Article
12. How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2018
    Article
13. Surveillance of the armed forces as a sentinel system for detecting adverse effects of dietary supplements in the general population.Public health nutrition · 2018
    Article
14. The use of nutritional guidance within chiropractic patient management: a survey of 333 chiropractors from the ACORN practice-based research network.Chiropractic & manual therapies · 2018
    Article

Corrections and comments

• Comment on
  Trends in Dietary Supplement Use Among US Adults From 1999-2012.2016

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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