ArticlePloS one2016
Relationship between Plasma Triglyceride Level and Severity of Hypertriglyceridemic Pancreatitis.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Tenth Special Issue.Journal of clinical apheresis · 2026Guideline
- Article
- Development and validation of a 24-h predictive model for hypertriglyceridemic moderately severe acute pancreatitis: a single-center retrospective study.Frontiers in medicine · 2026Article
- Article
- Predicting Severity in Hypertriglyceridemia-Induced Acute Pancreatitis: The Role of Neutrophils, Calcium, and Apolipoproteins.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- The role of apheresis and insulin therapy in hypertriglyceridemic acute pancreatitis-a concise review.BMC gastroenterology · 2023Review
- Effect of Plasma Exchange Treatment in Patients with Hypertriglyceridemia-Induced Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2023Article
- Comprehensive review on the pathogenesis of hypertriglyceridaemia-associated acute pancreatitis.Annals of medicine · 2023Review
- Rapidly lowering triglyceride levels by plasma exchange in acute pancreatitis: What's the point?Journal of clinical apheresis · 2022Article
- Development and validation of a prediction model for moderately severe and severe acute pancreatitis in pregnancy.World journal of gastroenterology · 2022Article
- Rapid reduction in triglyceride levels by therapeutic plasma exchange in patients with hypertriglyceridemic pancreatitis.Journal of clinical apheresis · 2022Article
- Tetrad of DKA, Hypertriglyceridemia Induced Pancreatitis and Splenic Vein Thrombosis.Journal of community hospital internal medicine perspectives · 2022Article
- Acute Pancreatitis in the Transgender Population.Cureus · 2021Article
- Negative Regulation of SIRT1 by IRF9 Involved in Hyperlipidemia Acute Pancreatitis Associated with Kidney Injury.Digestive diseases and sciences · 2021Article
- Article
- Total cholesterol concentration predicts the effect of plasmapheresis on hypertriglyceridemic acute pancreatitis: a retrospective case-control study.BMC gastroenterology · 2021Article
- The relationship between triglyceride level and the severity of acute hypertriglyceridemic pancreatitis in Chinese patients.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- High-density lipoprotein cholesterol to low-density lipoprotein cholesterol ratio in early assessment of disease severity and outcome in patients with acute pancreatitis admitted to the ICU.BMC gastroenterology · 2020Article
- Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles.Journal of the Endocrine Society · 2019Article
- The relationship between serum triglyceride levels and acute pancreatitis in an animal model and a 14-year retrospective clinical study.Lipids in health and disease · 2019Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertriglyceridemia is the third most common cause of acute pancreatitis, but whether the level of triglyceride (TG) is related to severity of pancreatitis is unclear.
aimTo evaluate the effect of TG level on the severity of hypertriglyceridemic pancreatitis (HTGP).
designRetrospective cohort study.
methodsWe reviewed the records of 144 patients with HTGP from 1999 to 2013 at Tri-Service General Hospital. Patients with possible etiology of pancreatitis, such as gallstones, those consuming alcohol or drugs, or those with infections were excluded. The classification of severity of pancreatitis was based on the revised Atlanta classification. We allocated the patients into high-TG and low-TG groups based on the optimal cut-off value (2648 mg/dL), which was derived from the receiver operating characteristic (ROC) curve between TG level and severity of HTGP. We then compared the clinical characteristics, pancreatitis severity, and mortality rates of the groups.
resultsThere were 66 patients in the low-TG group and 78 patients in the high-TG group. There was no significant difference in the age, sex ratio, body mass index, and comorbidity between the 2 groups. The high-TG group had significantly higher levels of glucose (P = 0.022), total cholesterol (P = 0.002), and blood urea nitrogen (P = 0.037), and lower levels of sodium (P = 0.003) and bicarbonate (P = 0.002) than the low-TG group. The incidences of local complication (P = 0.002) and severe and moderate form of pancreatitis (P = 0.004) were significantly higher in the high-TG group than in the low-TG group. The mortality rate was higher in the high-TG group than in the low-TG group (P = 0.07).
conclusionsHigher TG level in patients with HTGP may be associated with adverse prognosis, but randomized and prospective studies are needed in the future verify this relationship.
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