Evidence map›Paper›PMID 27726856›Full record

Observational studyThe Annals of thoracic surgery2017

Prediction of Transfusions After Isolated Coronary Artery Bypass Grafting Surgical Procedures.

Donald S Likosky, Theron A Paugh, Steven D Harrington, Xiaoting Wu, Mary A M Rogers, Timothy A Dickinson, Alphonse DeLucia, Barbara R Benedetti, Richard L Prager, Min Zhang and 2 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in The Annals of thoracic surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Guideline
  2. Article
  3. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  4. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Does Transfusion of Blood and Blood Products Increase the Length of Stay in Hospital?Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2019
    Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Donald S LikoskyDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan. Electronic address: likosky@umich.edu.
Theron A PaughDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Steven D HarringtonHeart and Vascular Institute, Henry Ford Macomb Hospitals, Clinton Township, Michigan.
Xiaoting WuDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Mary A M RogersDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Timothy A DickinsonDepartment of Surgery, Mayo Clinic, Rochester, Minnesota.
Alphonse DeLuciaDepartment of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan.
Barbara R BenedettiDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Richard L PragerDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Min ZhangDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan.
Gaetano PaoneDivision of Cardiac Surgery, Department of Surgery, Henry Ford Hospital, Detroit, Michigan.
Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative
University of Michigan–Ann Arbor · USBronson Methodist Hospital · USHenry Ford Hospital · USHenry Ford Macomb Hospital · USMayo Clinic · US

Funding

AHRQ HHS R03 HS022909
6 · The paper itself

Abstract

backgroundAlthough blood transfusions are common and have been associated with adverse sequelae after cardiac surgical procedures, few contemporaneous models exist to support clinical decision making. This study developed a preoperative clinical decision support tool to predict perioperative red blood cell transfusions in the setting of isolated coronary artery bypass grafting.

methodsWe performed a multicenter, observational study of 20,377 patients undergoing isolated coronary artery bypass grafting among patients at 39 hospitals participating in the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative's PERFusion measures and outcomes (PERForm) registry between 2011 and 2015. Candidates' preoperative risk factors were identified based on previous work and clinical input. The study population was randomly divided into a 70% development sample and a 30% validation sample. A generalized linear mixed-effect model was developed to predict perioperative red blood cell transfusion. The model's performance was assessed for calibration and discrimination. Sensitivity analysis was performed to assess the robustness of the model in different clinical subgroups.

resultsTransfusions occurred in 36.8% of patients. The final regression model included 16 preoperative variables. The correlation between the observed and expected transfusions was 1.0. The risk prediction model discriminated well (receiver operator characteristic [ROC]

conclusionsOur risk prediction model uses 16 readily obtainable preoperative variables. This model, which provides a patient-specific estimate of the need for transfusion, offers clinicians a guide for decision making and evaluating the effectiveness of blood management strategies.

Indexed as

Blood TransfusionClinical Decision-MakingCoronary Artery BypassNeeds AssessmentAgedCoronary Artery DiseaseFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesRisk AssessmentROC Curve

Identifiers

PMID27726856
PMCPMC5968351
OpenAlexW2529794894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.