Evidence map›Paper›PMID 27726794›Full record

ReviewMicrobiology spectrum2016

Surviving Between Hosts: Sporulation and Transmission.

Michelle C Swick, Theresa M Koehler, Adam Driks

Abstract readReview
In one paragraph

Review in Microbiology spectrum, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Approaching pathogenicbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Analysis of Sporulation inPathogens (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Expression profiles of sporulation genes in multidrug-resistantExperimental biology and medicine (Maywood, N.J.) · 2023
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Enigmatic Pilus-Like Endospore Appendages ofInternational journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle C SwickUniversity of Texas Medical School at Houston, Houston, TX 77030.
Theresa M KoehlerUniversity of Texas Medical School at Houston, Houston, TX 77030.
Adam DriksLoyola University Chicago, Stritch School of Medicine, Maywood, IL 60153.

Funding

VIRULENCE GENE EXPRESSION BY BACILLUS ANTHRACISR01AI033537 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOEHLER, THERESA M. · 1998 to 2020
$5.4M
A novel anti-spore nasal vaccine for protection from anthraxR01AI093493 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI DRIKS, ADAM, HOEPRICH, PAUL DANIEL · 2011 to 2015
$3.3M
NIAID NIH HHS R01 AI033537NIAID NIH HHS R01 AI093493
6 · The paper itself

Abstract

To survive adverse conditions, some bacterial species are capable of developing into a cell type, the "spore," which exhibits minimal metabolic activity and remains viable in the presence of multiple environmental challenges. For some pathogenic bacteria, this developmental state serves as a means of survival during transmission from one host to another. Spores are the highly infectious form of these bacteria. Upon entrance into a host, specific signals facilitate germination into metabolically active replicating organisms, resulting in disease pathogenesis. In this article, we will review spore structure and function in well-studied pathogens of two genera, Bacillus and Clostridium, focusing on Bacillus anthracis and Clostridium difficile, and explore current data regarding the lifestyles of these bacteria outside the host and transmission from one host to another.

Indexed as

AnimalsAnthraxBacillus anthracisClostridioides difficileClostridium InfectionsHumansSpores, Bacterial

Identifiers

PMID27726794
PMCPMC5062746

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.