Evidence map›Paper›PMID 27726639›Full record

ReviewOmics : a journal of integrative biology2016

Genetics of Sickle Cell-Associated Cardiovascular Disease: An Expert Review with Lessons Learned in Africa.

Amy Geard, Gift D Pule, David Chelo, Valentina Josiane Ngo Bitoungui, Ambroise Wonkam

Open access · greenAbstract readReview
In one paragraph

Review in Omics : a journal of integrative biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amy Geard1 Division of Human Genetics, Departments of Medicine and Pathology, Faculty of Health Sciences, University of Cape Town , Cape Town, South Africa .
Gift D Pule1 Division of Human Genetics, Departments of Medicine and Pathology, Faculty of Health Sciences, University of Cape Town , Cape Town, South Africa .
David Chelo2 Department of Paediatrics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé , Yaoundé, Cameroon .
Valentina Josiane Ngo Bitoungui3 Department of Hematology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé , Yaoundé, Cameroon .
Ambroise Wonkam1 Division of Human Genetics, Departments of Medicine and Pathology, Faculty of Health Sciences, University of Cape Town , Cape Town, South Africa .
University of Cape Town · ZA

Funding

Sickle Africa Data Coordinating CenterU24HL135600 · NHLBI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA, WONKAM, AMBROISE · 2017 to 2025
$8.6M
Exploring Perspectives on Genomics and Sickle Cell Public Health InterventionsU01HG007459 · NHGRI · UNIVERSITY OF CAPE TOWN · PI WONKAM, AMBROISE · 2013 to 2016
$622k
NHGRI NIH HHS U01 HG007459NHLBI NIH HHS U24 HL135600Wellcome Trust 107755Z/15/Z
6 · The paper itself

Abstract

Sickle cell disease (SCD) vastly impacts the African continent and is associated with cardiovascular diseases. Stroke, kidney disease, and pulmonary hypertension are considered as proxies of severity in SCD with several genomic loci implicated in their heritability. The present expert review examined the current data on epidemiology and genetic risk factors of stroke, pulmonary hypertension, and kidney disease associated with SCD, as indexed in PubMed

Indexed as

Precision MedicineAfricaAnemia, Sickle CellCardiovascular DiseasesGenome-Wide Association StudyHumansKidney DiseasesAfricaglobal precision medicinekidney diseasepulmonary hypertensionsickle cell diseasestroke

Identifiers

PMID27726639
PMCPMC5067873
OpenAlexW2558879823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.