Evidence map›Paper›PMID 27726428›Full record

ReviewAIDS research and human retroviruses

Understanding the Intersection of Young Age, Mucosal Injury, and HIV Susceptibility.

Kristen A Porter, Jim Turpin, Lisa Begg, Gina Brown, Nahida Chakhtoura, Elizabeth Church, Cynthia Grossman, Charles Wira, Fulvia Veronese

Abstract readReview
In one paragraph

Review in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Sexually Transmitted Infection Testing After Brief Intervention for Risk Behaviors in School-Based Health Centers.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Trial
  2. Trial
  3. The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kristen A Porter1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
Jim Turpin1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
Lisa Begg2 Office of Research on Women's Health, National Institutes of Health , Bethesda, Maryland.
Gina Brown3 Office of AIDS Research, National Institutes of Health , Bethesda, Maryland.
Nahida Chakhtoura4 Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, Maryland.
Elizabeth Church1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
Cynthia Grossman5 Division of AIDS Research, National Institute of Mental Health, National Institutes of Health , Rockville, Maryland.
Charles Wira6 Geisel School of Medicine, Dartmouth College , Hanover, New Hampshire.
Fulvia Veronese1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USDartmouth College · US

Funding

Chemical Contraceptive Control of Microbicides in the Female Reproductive TractR01AI117739 · NIAID · DARTMOUTH COLLEGE · PI WIRA, CHARLES ROBERT · 2015 to 2018
$2.6M
NIAID NIH HHS R01 AI117739
6 · The paper itself

Abstract

Adolescent boys and girls are disproportionately affected in the current HIV epidemic. Numerous sociobehavioral studies have addressed the indirect drivers surrounding this vulnerability-for example, socioeconomic, geographical locale, and all forms of violence. However, the direct factors that may influence infection, such as the anatomical and physiological maturation of the anogenital tracts of adolescents or the trauma and wound-healing processes of injured mucosal tissue, are understudied and represent a gap within the HIV prevention field. This article reviews the epidemiology of HIV infection and violence in adolescents and the available basic science knowledge attending this research area. More importantly, this review highlights the most critical gaps that need to be addressed to design preventive interventions that are safe and effective for this population, which is key to ending the HIV pandemic.

Indexed as

Age FactorsDisease SusceptibilityWound HealingAdolescentFemaleHIV InfectionsHumansMaleMucous MembraneSex OffensesYoung AdultHIVHIV/AIDS pathogenesisHIV preventionHIV transmissionmucosal

Identifiers

PMID27726428
PMCPMC6445180
OpenAlexW2558195503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.