ArticleAngewandte Chemie (International ed. in English)2016
Bilayer Networks within a Hydrogel Shell: A Robust Chassis for Artificial Cells and a Platform for Membrane Studies.
Article in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Prototissues: Assembly strategies, collective behaviors, and emerging applications.Bioactive materials · 2026Review
- Biomolecular Neuristors from Functionalized Lipid Membranes.Advanced functional materials · 2024Article
- Manipulation of encapsulated artificial phospholipid membranes using sub-micellar lysolipid concentrations.Communications chemistry · 2024Article
- Nanoparticle transport in biomimetic polymer-linked emulsions.AIChE journal. American Institute of Chemical Engineers · 2024Article
- A microscale soft lithium-ion battery for tissue stimulation.Nature chemical engineering · 2024Article
- Signal processing and generation of bioactive nitric oxide in a model prototissue.Nature communications · 2022Article
- Microfluidics Fabrication of Micrometer-Sized Hydrogels with Precisely Controlled Geometries for Biomedical Applications.Advanced healthcare materials · 2022Review
- Encapsulated droplet interface bilayers as a platform for high-throughput membrane studies.Soft matter · 2022Article
- Chemical-mediated translocation in protocell-based microactuators.Nature chemistry · 2021Article
- Droplet Microfluidics for Tumor Drug-Related Studies and Programmable Artificial Cells.Global challenges (Hoboken, NJ) · 2021Review
- Crosslinking Strategies for the Microfluidic Production of Microgels.Molecules (Basel, Switzerland) · 2021Review
- Bioluminescent detection of isothermal DNA amplification in microfluidic generated droplets and artificial cells.Scientific reports · 2020Article
- Microfluidic platform enables tailored translocation and reaction cascades in nanoliter droplet networks.Communications biology · 2020Article
- Development of Artificial Cell Models Using Microfluidic Technology and Synthetic Biology.Micromachines · 2020Review
- Formation of Polarized, Functional Artificial Cells from Compartmentalized Droplet Networks and Nanomaterials, Using One-Step, Dual-Material 3D-Printed Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Synthetic tissues.Emerging topics in life sciences · 2019Article
- Creation of Artificial Cell-Like Structures Promoted by Microfluidics Technologies.Micromachines · 2019Review
- Controlled Construction of Stable Network Structure Composed of Honeycomb-Shaped Microhydrogels.Life (Basel, Switzerland) · 2018Article
- Encapsulating Networks of Droplet Interface Bilayers in a Thermoreversible Organogel.Scientific reports · 2018Article
- Hierarchical Self-Assembly of a Copolymer-Stabilized Coacervate Protocell.Journal of the American Chemical Society · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to make artificial lipid bilayers compatible with a wide range of environments, and with sufficient structural rigidity for manual handling, would open up a wealth of opportunities for their more routine use in real-world applications. Although droplet interface bilayers (DIBs) have been demonstrated in a host of laboratory applications, from chemical logic to biosynthesis reaction vessels, their wider use is hampered by a lack of mechanical stability and the largely manual methods employed in their production. Multiphase microfluidics has enabled us to construct hierarchical triple emulsions with a semipermeable shell, in order to form robust, bilayer-bound, droplet networks capable of communication with their external surroundings. These constructs are stable in air, water, and oil environments and overcome a critical obstacle of achieving structural rigidity without compromising environmental interaction. This paves the way for practical application of artificial membranes or droplet networks in diverse areas such as medical applications, drug testing, biophysical studies and their use as synthetic cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.