Evidence map›Paper›PMID 27726243›Full record

ArticleHuman brain mapping2017

Simultaneous total intracranial volume and posterior fossa volume estimation using multi-atlas label fusion.

Yuankai Huo, Andrew J Asman, Andrew J Plassard, Bennett A Landman

Abstract read
In one paragraph

Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Hippocampal Total, Subregion, and Subfield Volume Alterations in Late-Life Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
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  5. Structural brain differences in essential tremor and Parkinson's disease deep brain stimulation patients.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2023
    Observational
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  11. Structural Correlates of the Sensorimotor Cerebellum in Parkinson's Disease and Essential Tremor.Movement disorders : official journal of the Movement Disorder Society · 2020
    Article
  12. Generalizing Deep Whole Brain Segmentation for Pediatric and Post- Contrast MRI with Augmented Transfer Learning.Proceedings of SPIE--the International Society for Optical Engineering · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Reproducibility Evaluation of SLANT Whole Brain Segmentation Across Clinical Magnetic Resonance Imaging Protocols.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  17. Article
  18. Article
  19. Multi-atlas Parcellation in the Presence of Lesions: Application to Multiple Sclerosis.Patch-based techniques in medical imaging : 4th international workshop, Patch-MI 2018, held in conjunction with MICCAI 2018, Granada, Spain, September 20, 2018 : proceedings. Patch-MI (Workshop) (4th : 2018 : Granada, Spain) · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuankai HuoElectrical Engineering, Vanderbilt University, Nashville, Tennessee.
Andrew J AsmanElectrical Engineering, Vanderbilt University, Nashville, Tennessee.
Andrew J PlassardComputer Science, Vanderbilt University, Nashville, Tennessee.
Bennett A LandmanElectrical Engineering, Vanderbilt University, Nashville, Tennessee.

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Controlling Quality and Capturing Uncertainty in Advanced Diffusion Weighted MRIR01EB017230 · NIBIB · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2015 to 2024
$5.1M
Computer-Assisted functional neurosurgeryR01EB006136 · NIBIB · VANDERBILT UNIVERSITY · PI DAWANT, BENOIT M. · 2006 to 2013
$4.0M
Automatic Cerebellar MRI Labeling In Health and DiseaseR01NS056307 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2006 to 2015
$3.0M
Computer-Assited Functional NeurosurgeryR01NS095291 · NINDS · VANDERBILT UNIVERSITY · PI DAWANT, BENOIT M., DHAESE, PIERRE F. · 2015 to 2018
$2.4M
Brain Image Analysis Tools for Quantitative Longitudinal Assessment of MSR01NS070906 · NINDS · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI PHAM, DZUNG L · 2010 to 2014
$1.7M
BIDS: Vanderbilt Training Program in BIg Biomedical Data ScienceT32LM012412 · NLM · VANDERBILT UNIVERSITY · PI BLUME, JEFFREY D., GADD, CYNTHIA S · 2016 to 2020
$1.5M
Autosegmentation for head and neck RadiotherapyR01EB006193 · NIBIB · VANDERBILT UNIVERSITY · PI DAWANT, BENOIT M. · 2007 to 2010
$1.4M
An Interactive Web-Based Game for Collaborative Labeling of Medical ImagesR21NS064534 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2009 to 2010
$436k
Segmentation and volumetric quantification of thalamic nuclei for assessing MSR21NS082891 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2013 to 2014
$425k
Quantitative Image Analysis Techniques for Optic Nerve DiseaseR21EY024036 · NEI · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2014 to 2015
$410k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NEI NIH HHS R21 EY024036NIBIB NIH HHS R01 EB006136NIBIB NIH HHS R01 EB006193NIBIB NIH HHS R01 EB017230NIBIB NIH HHS R03 EB012461NINDS NIH HHS R01 NS056307NINDS NIH HHS R01 NS070906NINDS NIH HHS R01 NS095291NINDS NIH HHS R21 NS064534NINDS NIH HHS R21 NS082891NLM NIH HHS T32 LM012412
6 · The paper itself

Abstract

Total intracranial volume (TICV) is an essential covariate in brain volumetric analyses. The prevalent brain imaging software packages provide automatic TICV estimates. FreeSurfer and FSL estimate TICV using a scaling factor while SPM12 accumulates probabilities of brain tissues. None of the three provide explicit skull/CSF boundary (SCB) since it is challenging to distinguish these dark structures in a T1-weighted image. However, explicit SCB not only leads to a natural way of obtaining TICV (i.e., counting voxels inside the skull) but also allows sub-definition of TICV, for example, the posterior fossa volume (PFV). In this article, they proposed to use multi-atlas label fusion to obtain TICV and PFV simultaneously. The main contributions are: (1) TICV and PFV are simultaneously obtained with explicit SCB from a single T1-weighted image. (2) TICV and PFV labels are added to the widely used BrainCOLOR atlases. (3) Detailed mathematical derivation of non-local spatial STAPLE (NLSS) label fusion is presented. As the skull is clearly distinguished in CT images, we use a semi-manual procedure to obtain atlases with TICV and PFV labels using 20 subjects who both have a MR and CT scan. The proposed method provides simultaneous TICV and PFV estimation while achieving more accurate TICV estimation compared with FreeSurfer, FSL, SPM12, and the previously proposed STAPLE based approach. The newly developed TICV and PFV labels for the OASIS BrainCOLOR atlases provide acceptable performance, which enables simultaneous TICV and PFV estimation during whole brain segmentation. The NLSS method and the new atlases have been made freely available. Hum Brain Mapp 38:599-616, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

Atlases as TopicImage Interpretation, Computer-AssistedNeuroimagingPattern Recognition, AutomatedAlgorithmsBrainHumansModels, StatisticalSkullintracranial volumelabel fusionmulti-atlas segmentationNLSSnon-local spatial stapleposterior fossaTICV

Identifiers

PMID27726243
PMCPMC5225112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.