ArticleJournal of clinical laboratory analysis2017
Diagnostic and prognostic value of galectin-3, serum creatinine, and cystatin C in chronic kidney diseases.
Article in Journal of clinical laboratory analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Beyond traditional biomarkers: do serum cystatin C and urinary cystatin B improve diagnostic precision in feline and canine renal disease? A systematic review and meta-analysis.Frontiers in veterinary science · 2026Pooled it
- Galectin-3: Integrator of Signaling via Hexosamine Flux.Biomolecules · 2025Review
- The potential roles of galectin-3 in AKI and CKD.Frontiers in physiology · 2023Review
- Galectin-3-A New Player of Kidney Damage or an Innocent Bystander in Children with a Single Kidney?Journal of clinical medicine · 2021Article
- Serum galectin-3 level as a marker for diagnosis and prognosis of neonatal necrotising enterocolitis: a cohort study.American journal of translational research · 2021Article
- Value of elastography point quantification in improving the diagnostic accuracy of early diabetic kidney disease.World journal of clinical cases · 2019Article
- Elevated preoperative Galectin-3 is associated with acute kidney injury after cardiac surgery.BMC nephrology · 2018Article
- GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Observational
- Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review).International journal of molecular medicine · 2018Review
- Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation.Journal of clinical laboratory analysis · 2017Article
- Establishing the presence or absence of chronic kidney disease: Uses and limitations of formulas estimating the glomerular filtration rate.World journal of methodology · 2017Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study was undertaken to determine the diagnostic and prognostic values of galectin-3 (Gal-3) in patients with chronic kidney disease (CKD).
methodsPatients with CKD (n=150) were enrolled as the CKD group, which was divided into six groups according to glomerular filtration rates (GFR) indexes. At the same time, 50 healthy adults were chosen for the control group (NC). Measured data included the levels of serum Gal-3, serum creatinine (SCr), β
resultsThere was no significant difference between CKD and NC group in age, gender and the level of Alb. CKD group had lower estimated glomerular filtration rate (eGFR) but higher Gal-3, CysC, SCr, β
conclusionsOur study verified Gal-3, CysC and SCr were negatively related to eGFR. Besides, it is suggested that Gal-3 can be used as an indicating factor in the diagnosis of CKD; the joint analysis of Gal-3, CysC and SCr for CKD may distinctly improve diagnostic accuracy.
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Registered trials
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