Evidence map›Paper›PMID 27726097›Full record

ArticleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016

Dendritic cells loading autologous tumor lysate promote tumor angiogenesis.

Yi Yang, Jing Lu, Hangfan Liu, Guoguo Jin, Ruihua Bai, Xiang Li, Dongyu Wang, Jimin Zhao, Youtian Huang, Kangdong Liu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Influence of ovarian cancer type I and type II microenvironment on the phenotype and function of monocyte-derived dendritic cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yi YangDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Jing LuDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.ORCID 0000-0002-9568-0031
Hangfan LiuDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Guoguo JinDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Ruihua BaiDepartment of Pathology, Henan Cancer Hospital, Zhengzhou University, Zhengzhou, Henan, 450008, People's Republic of China.
Xiang LiDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Dongyu WangDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Jimin ZhaoDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Youtian HuangDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Kangdong LiuDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China.
Ying XingDepartment of Physiology, Basic Medical College, Zhengzhou University, Zhengzhou, Henan, 450001, People's Republic of China. xingy@zzu.edu.cn.
Ziming DongDepartment of Pathophysiology, Basic Medical College, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. dongzm@zzu.edu.cn.
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DC) have been exploited for vaccination against cancer for years. DC loading autologous tumor lysate (ATL-DC) have been assessed in ongoing clinical trials, but frequently do not meet expectation. In this study, we found that mice immunized with ATL-DC induced less protective anti-tumor effect than immunized with DC alone. The percentage of CD8

Indexed as

Dendritic cellsHUVECTumor angiogenesisTumor lysateTumor vaccine

Identifiers

PMID27726097
OpenAlexW2530062779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.