Evidence map›Paper›PMID 27726053›Full record

ReviewMetabolic brain disease2016

Neuroinflammation in liver disease: sessional talks from ISHEN.

Gavin Wright, Mark Swain, Djillali Annane, Faouzi Saliba, Didier Samuel, Vicente Arroyo, Sharon DeMorrow, Anne Witt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Metabolic brain disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Recent Updates on Acquired Hepatocerebral Degeneration.Tremor and other hyperkinetic movements (New York, N.Y.) · 2017
    Review
  5. Review
  6. Brain Edema in Chronic Hepatic Encephalopathy.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gavin WrightGastroenterology Department, Basildon & Thurrock University Hospitals, Basildon, UK. Gavin.Wright@btuh.nhs.uk.
Mark SwainDivision of Gastroenterology and Hepatology, University of Calgary, Calgary, Canada.
Djillali AnnaneINSERM CIC IT 805, CHU Paris IdF Ouest - Hôpital Raymond Poincaré, 104 boulevard Raymond Poincaré, 92380, Garches, France.
Faouzi SalibaCentre Hépato-Biliaire, Hôpital Paul Brousse, 12, avenue Paul vaillant Couturier, 94800, Villejuif, France.
Didier SamuelGHU Paris-Sud - Hôpital Paul Brousse, 12 avenue Paul Vaillant-Couturier, 94804, Villejuif Cedex, France.
Vicente ArroyoLiver Unit, Instiute of Digestive and Metabolic Diseases, Hopsital Clinic, University of Barcelona, Barcelona, Spain.
Sharon DeMorrowDepartment of Internal Medicine, Central Texas Veterans Healthcare System, VA Bld 205, 1901 South 1st Street, Temple, TX, 76504, USA.
Anne WittDepartement of Hepatology, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the recent ISHEN ('International Symposium of Hepatic Encephalopathy & Nitrogen Metabolism') conference in London, a whole session was dedicated to our increasing awareness of the importance of inflammation in the brain - termed 'neuroinflammation', in the development of Hepatic Encephalopathy (HE) - the neurological manifestations of advanced liver disease. In this review our ISHEN speakers further discuss the content of their sessional presentations and more broadly we discuss our understanding of the role of neuroinflammation in HE pathogenesis.

Indexed as

Congresses as TopicInternationalityAnimalsBlood-Brain BarrierBrainHepatic EncephalopathyHumansInflammationInflammation MediatorsLiver DiseasesInflammation MediatorsAmmoniaCerebral HeamodynamicsCompensatory Antiinflammatory responsesLiver failureNeuroinflammationSystemic inflammatory responses

Identifiers

PMID27726053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.