Evidence map›Paper›PMID 27726040›Full record

ArticleLasers in medical science2017

Effects of photobiomodulation therapy, pharmacological therapy, and physical exercise as single and/or combined treatment on the inflammatory response induced by experimental osteoarthritis.

Shaiane Silva Tomazoni, Ernesto Cesar Pinto Leal-Junior, Rodney Capp Pallotta, Simone Teixeira, Patricia de Almeida, Rodrigo Álvaro Brandão Lopes-Martins

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06122116 (Investigating Orthobiologics After Platelet-Rich Plasma and Photobiomodulation Treatment of Knee Osteoarthritis), which is not on this map. Cited by 58 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 7 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06122116 naterminatednot on this mapstarted 2023, after this paper: background citation

Investigating Orthobiologics After Platelet-Rich Plasma and Photobiomodulation Treatment of Knee Osteoarthritis

TypeinterventionalSponsorMusculoskeletal Injury Rehabilitation Research for Operational ReadinessRan2023 to 2024Enrolled33ConditionsKnee OsteoarthritisArmsPhysical Therapy, Platelet-Rich Plasma Injection, Photobiomodulation Therapy
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 7 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  3. Cartilage · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shaiane Silva TomazoniLaboratory of Pharmacology and Experimental Therapeutics, Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), Av. Prof. Lineu Prestes, 1524, Butantan, São Paulo, SP, 05508-900, Brazil. shaiane.tomazoni@gmail.com.
Ernesto Cesar Pinto Leal-JuniorPostgraduate Program in Biophotonics Applied to Health Sciences and Post Graduate Program in Rehabilitation Sciences, Nove de Julho University (UNINOVE), São Paulo, SP, Brazil.
Rodney Capp PallottaLaboratory of Pharmacology and Experimental Therapeutics, Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), Av. Prof. Lineu Prestes, 1524, Butantan, São Paulo, SP, 05508-900, Brazil.
Simone TeixeiraLaboratory of Pharmacology and Experimental Therapeutics, Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), Av. Prof. Lineu Prestes, 1524, Butantan, São Paulo, SP, 05508-900, Brazil.
Patricia de AlmeidaLaboratory of Pharmacology and Experimental Therapeutics, Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), Av. Prof. Lineu Prestes, 1524, Butantan, São Paulo, SP, 05508-900, Brazil.
Rodrigo Álvaro Brandão Lopes-MartinsBiomedical Engineering Research and Post-Graduate Center, Mogi das Cruzes University (UMC), Mogi das Cruzes, SP, Brazil.
Universidade de São Paulo · BRUniversidade de Mogi das Cruzes · BRUniversidade Nove de Julho · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) triggers increased levels of inflammatory markers, including prostaglandin (PG) E

Indexed as

Low-Level Light TherapyPhysical Conditioning, AnimalAnimalsAnti-Inflammatory Agents, Non-SteroidalCombined Modality TherapyDinoprostoneDisease Models, AnimalEnzyme-Linked Immunosorbent AssayGene Expression RegulationHumansInflammationInterleukin-1betaInterleukin-6Knee JointMaleOsteoarthritisAnti-Inflammatory Agents, Non-SteroidalDinoprostoneInterleukin-1betaInterleukin-6Tumor Necrosis Factor-alphaNonsteroidal antiinflammatory drugOsteoarthritisPapainPhotobiomodulation therapyPhysical exerciseRats

Identifiers

PMID27726040
OpenAlexW2530369399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.