Evidence map›Paper›PMID 27725960›Full record

ArticleACS central science2016

Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes.

Jian Yang, Azadeh Bahreman, Geert Daudey, Jeroen Bussmann, René C L Olsthoorn, Alexander Kros

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS central science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Review
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  6. Frontiers in cell and developmental biology · 2026
    Review
  7. Article
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  15. Review
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian YangDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.
Azadeh BahremanDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.
Geert DaudeyDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.
Jeroen BussmannDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.
René C L OlsthoornDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.
Alexander KrosDepartment of Supramolecular Chemistry & Biomaterials, Leiden Institute of Chemistry, Leiden University , P.O. Box 9502, Leiden, 2300 RA, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient delivery of drugs to living cells is still a major challenge. Currently, most methods rely on the endocytotic pathway resulting in low delivery efficiency due to limited endosomal escape and/or degradation in lysosomes. Here, we report a new method for direct drug delivery into the cytosol of live cells

Identifiers

PMID27725960
PMCPMC5043431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.