ArticleInternal medicine (Tokyo, Japan)
Chronic Hepatitis E Infection in a Persistently Immunosuppressed Patient Unable to Be Eliminated after Ribavirin Therapy.
Article in Internal medicine (Tokyo, Japan). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Seroprevalence and determinants of hepatitis E virus infection among people living with HIV in Chiang Mai, Thailand: a cross-sectional analysis.Scientific reports · 2026Article
- Assessment of Hepatitis E virus transmission risks: a comprehensive review of cases among blood transfusion recipients and blood donors.Infection ecology & epidemiology · 2024Review
- The Diagnosis, Pathophysiology, and Treatment of Chronic Hepatitis E Virus Infection-A Condition Affecting Immunocompromised Patients.Microorganisms · 2023Review
- Chronic hepatitis E in an elderly immunocompetent patient who achieved a sustained virologic response with ribavirin treatment.Clinical journal of gastroenterology · 2023Article
- Shear wave elastography-based liver fibrosis assessment in patients with chronic hepatitis E displays elevated liver stiffness regardless of previous antiviral therapy.Quantitative imaging in medicine and surgery · 2022Article
- Genetic diversity of hepatitis E virus (HEV) in imported and domestic camels in Saudi Arabia.Scientific reports · 2022Article
- Review
- Hepatitis E in Sub Saharan Africa - A significant emerging disease.One health (Amsterdam, Netherlands) · 2021Review
- Seroprevalence of Dromedary Camel HEV in Domestic and Imported Camels from Saudi Arabia.Viruses · 2020Article
- The spontaneous clearance of hepatitis E virus (HEV) and emergence of HEV antibodies in a transfusion-transmitted chronic hepatitis E case after completion of chemotherapy for acute myeloid leukemia.Clinical journal of gastroenterology · 2020Article
- Chronic Hepatitis E is associated with cholangitis.Liver international : official journal of the International Association for the Study of the Liver · 2019Article
- Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus.Journal of clinical and translational hepatology · 2018Review
- Transfusion-Transmitted Hepatitis E: NAT Screening of Blood Donations and Infectious Dose.Frontiers in medicine · 2018Article
- Vaccine Development against Zoonotic Hepatitis E Virus: Open Questions and Remaining Challenges.Frontiers in microbiology · 2018Review
- Hepatitis E: Update on Prevention and Control.BioMed research international · 2018Review
- Severe hepatitis E virus genotype 3b in a patient with alcohol‑associated liver disease: A case report.Medicine internationalArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent case reports have shown that hepatitis E virus (HEV) infection can cause chronic hepatitis in immunosuppressed or immunocompromised patients. A 37-year-old woman suffered from prolonged elevation of aminotransferases after chemotherapy for Burkitt's lymphoma and was diagnosed with chronic hepatitis E due to a transfusion during chemotherapy. After an 8-month administration of ribavirin, complete HEV clearance was not achieved, likely due to prolonged hypogammaglobulinemia. This case indicates that HEV infection should be ruled out during liver dysfunction in immunosuppressed or immunocompromised patients and suggests that an alternative therapeutic strategy for such patients will be needed.
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