ReviewThe Journal of veterinary medical science2017
Immune exhaustion during chronic infections in cattle.
Review in The Journal of veterinary medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Combinations of long terminal repeat and tax protein substitutions influence bovine leukemia virus transmission through altered viral productivity.Microbiology spectrum · 2026Article
- Generation of anti-bovine CD20 monoclonal antibody with cytotoxic activity for the depletion of bovine B-cell lymphoma cells.Scientific reports · 2026Article
- Exhausted CD4Frontiers in immunology · 2026Article
- First Identification ofPathogens (Basel, Switzerland) · 2025Article
- The Complexity of Bovine Leukemia Virus Oncogenesis.Viruses · 2025Review
- Polymorphism ofPathogens (Basel, Switzerland) · 2025Article
- Evaluation of Immune Exhaustion and Co-Inhibitory Receptor Expression inPathogens (Basel, Switzerland) · 2024Article
- Periparturient blood T-lymphocyte PD-1 and CTLA-4 expression as potential predictors of new intramammary infections in dairy cows during early lactation (short communication).BMC veterinary research · 2024Article
- The role, relevance and management of immune exhaustion in bovine infectious diseases.Heliyon · 2024Review
- Milk exosomal microRNA profiling identified miR-375 and miR-199-5p for regulation of immune response during subclinical mastitis of crossbred cattle.Molecular biology reports · 2024Article
- Prophylactic treatment with PEGylated bovine IFNλ3 effectively bridges the gap in vaccine-induced immunity against FMD in cattle.Frontiers in microbiology · 2024Article
- Characterization of the adaptive cellular and humoral immune responses to persistent colonization ofFrontiers in veterinary science · 2024Article
- Article
- The bovine leukemia virus-derived long non-coding RNA AS1-S binds to bovine hnRNPM and alters the interaction between hnRNPM and host mRNAs.Microbiology spectrum · 2023Article
- Combined Immune Checkpoint Blockade Enhances Antiviral Immunity against Bovine Leukemia Virus.Journal of virology · 2023Article
- Prostaglandin EInfection and immunity · 2022Article
- Single-Nucleotide Polymorphism on Spermatogenesis Associated 16 Gene-Coding Region Affecting Bovine Leukemia Virus Proviral Load.Veterinary sciences · 2022Article
- Estradiol-induced immune suppression via prostaglandin E2 during parturition in bovine leukemia virus-infected cattle.PloS one · 2022Article
- Brief Research Report: Expression of PD-1 and CTLA-4 in T Lymphocytes and Their Relationship With the Periparturient Period and the Endometrial Cytology of Dairy Cows During the Postpartum Period.Frontiers in veterinary science · 2022Article
- Risk Assessment of Bovine Major Histocompatibility Complex Class IIPathogens (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, dysfunction of antigen-specific T cells is well documented as T-cell exhaustion and has been defined by the loss of effector functions during chronic infections and cancer in human. The exhausted T cells are characterized phenotypically by the surface expression of immunoinhibitory receptors, such as programmed death 1 (PD-1), lymphocyte activation gene 3 (LAG-3), T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) and cytotoxic T-lymphocyte antigen 4 (CTLA-4). However, there is still a fundamental lack of knowledge about the immunoinhibitory receptors in the fields of veterinary medicine. In particular, very little is known about mechanism of T cell dysfunction in chronic infection in cattle. Recent our studies have revealed that immunoinhibitory molecules including PD-1/ programmed death-ligand 1 (PD-L1) play critical roles in immune exhaustion and disease progression in case of bovine leukemia virus (BLV) infection, Johne's disease and bovine anaplasmosis. This review includes some recent data from us.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.