Evidence map›Paper›PMID 27725002›Full record

ArticleInternational psychogeriatrics2017

Cohort effects in verbal memory function and practice effects: a population-based study.

Hiroko H Dodge, Jian Zhu, Tiffany F Hughes, Beth E Snitz, Chung-Chou H Chang, Erin P Jacobsen, Mary Ganguli

Open access · diamondAbstract read
In one paragraph

Article in International psychogeriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
  6. Article
  7. Cohort Changes and Sex Differences After Age 50 in Cognitive Variables in the English Longitudinal Study of Ageing.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
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  12. A New Look at Cohort Trend and Underlying Mechanisms in Cognitive Functioning.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Depression Symptoms Declining Among Older Adults: Birth Cohort Analyses From the Rust Belt.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020
    Article
  17. Declining Incident Dementia Rates Across Four Population-Based Birth Cohorts.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hiroko H DodgeDepartment of Neurology,Michigan Alzheimer's Disease Center,University of Michigan,Ann Arbor,Michigan,USA.
Jian ZhuDepartment of Biostatistics,School of Public Health,University of Michigan,Ann Arbor,Michigan,USA.
Tiffany F HughesYoungstown State University,One University Plaza,Youngstown,Ohio,USA.
Beth E SnitzDepartment of Neurology,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA.
Chung-Chou H ChangDepartment of Medicine,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA.
Erin P JacobsenDepartment of Psychiatry,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA.
Mary GanguliDepartment of Neurology,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA.
University of Pittsburgh · USOregon Health & Science University · USUniversity of Michigan–Ann Arbor · USYoungstown State University · US

Funding

Outreach, Recruitment and Education CoreP30AG008017 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 1990 to 2019
$27.7M
Mild Cognitive Impairment: A Prospective Community StudyR01AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2005 to 2020
$27.1M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
Study Coordination and Measurement CoreP01AG043362 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HOFER, SCOTT M., KAYE, JEFFREY A · 2013 to 2017
$7.8M
Epidemiology of Aging Brain and BehaviorK07AG044395 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2013 to 2017
$615k
NIA NIH HHS K07 AG044395NIA NIH HHS P01 AG043362NIA NIH HHS P30 AG008017NIA NIH HHS P30 AG053760NIA NIH HHS R01 AG023651
6 · The paper itself

Abstract

backgroundIn many developed countries, cognitive functioning (as measured by neuropsychological tests) appears to be improving over time in the population at large, in parallel with the declining age-specific incidence of dementia. Here, we investigated cohort effects in the age-associated trajectories of verbal memory function in older adults. We sought to determine whether they varied by decade of birth and, if so, whether the change would be explained by increasing educational attainment.

methodsPooling data from two prospective US population-based studies between 1987 and 2015, we identified four birth cohorts born 1902-1911, 1912-1921, 1922-1931, and 1932-1943. Among these cohorts, we compared age-associated trajectories both of performance and of practice effects on immediate and delayed recall of a 10-item Word List. We used mixed effects models, first including birth cohorts and cohort X age interaction terms, and then controlling for education and education X age interaction.

resultsWe observed significant cohort effects in performance (baseline and age-associated trajectories) in both immediate recall and delayed recall, with function improving between the earliest- and latest-born cohorts. For both tests, we also observed cohort effects on practice effects with the highest levels in the latest-born cohorts. Including education in the models did not attenuate these effects.

conclusionsIn this longitudinal population study, across four decade-long birth cohorts, there were significant improvements in test performance and practice effects in verbal memory tests, not explained by education. Whether this reflects declining disease incidence or other secular trends awaits further investigation.

Indexed as

Cohort EffectAgedAged, 80 and overAgingCognitionFemaleHumansLogistic ModelsLongitudinal StudiesMaleMemory, Short-TermNeuropsychological TestsPennsylvaniaProspective StudiesSurveys and Questionnairescognitive testingneuropsychological testing

Identifiers

PMID27725002
PMCPMC5177461
OpenAlexW2531187298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.