ArticleBMC cancer2016
Risk factors for cancer development in type 2 diabetes: A retrospective case-control study.
Article in BMC cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 45 citations in OpenAlex.
- Diabetes and cancer: therapeutic implications.Cardio-oncology (London, England) · 2026Review
- Association between glucose levels and all-cause mortality in cancer survivors: findings from NHANES 1999-2018.BMC public health · 2024Article
- Global, regional, and national time trends in cancer mortality attributable to high fasting plasma glucose: an age-period cohort analysis.BMC public health · 2023Article
- Alterations of Gut Mycobiota Profiles in Adenoma and Colorectal Cancer.Frontiers in cellular and infection microbiology · 2022Article
- Clinical Implication of Metformin in Relation to Diabetes Mellitus and Ovarian Cancer.Biomedicines · 2021Review
- Diabetes, Antidiabetic Medications and Cancer Risk in Type 2 Diabetes: Focus on SGLT-2 Inhibitors.International journal of molecular sciences · 2021Review
- Hyperglycemia and Chemoresistance in Breast Cancer: From Cellular Mechanisms to Treatment Response.Frontiers in oncology · 2021Review
- Increasing risk of diabetes mellitus in postmenopausal women with newly diagnosed primary breast cancer.Journal of diabetes investigation · 2020Article
- Prospective study of cancer in Japanese patients with type 2 diabetes: the Fukuoka Diabetes Registry.Diabetology international · 2019Article
- Effects of hyperglycemia on the progression of tumor diseases.Journal of experimental & clinical cancer research : CR · 2019Review
- Association of metabolic NCD risk factors with oral, breast and cervical precancers and cancers in India.Family medicine and community health · 2019Article
- Alpha-glucosidase inhibitors and risk of cancer in patients with diabetes mellitus: a systematic review and meta-analysis.Oncotarget · 2017Article
- Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective case-control study.Oncotarget · 2017Article
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk of several types of cancer is increased in type 2 diabetes mellitus. The earliest possible diagnosis of cancer - difficult within regular outpatient diabetes care - is of utmost importance for patients' survival. The aim of this multicenter, retrospective (years 1998-2015), case-control study was to identify risk factors associated with malignancy in subjects with diabetes treated in a typical outpatient setting.
methodsIn the databases of 3 diabetic and 1 primary care clinics 203 patients (115 women) with type 2 diabetes mellitus who developed malignancy while treated for diabetes were identified. The control group consisted of 203 strictly age- and gender matched subjects with type 2 diabetes without cancer. Factors associated with diabetes: disease duration, antidiabetic medications use and metabolic control of diabetes were analyzed. Also other variables: BMI (body mass index), smoking habits, place of residence and comorbidities were included into analysis.
resultsThe most prevalent malignancies in men and women together were breast cancer (20.7 %) and colorectal cancer (16.3 %). HbA
conclusionsIn the outpatient setting the obese patients with poorly controlled insulin treated type 2 diabetes mellitus should be rigorously assessed towards malignancies, particularly breast cancer in women and colorectal cancer in men.
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