Evidence map›Paper›PMID 27723665›Full record

ArticleAnatolian journal of cardiology2016

ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in non-valvular atrial fibrillation (RAMSES study).

Özcan Başaran, Osman Beton, Volkan Doğan, Mehmet Tekinalp, Ahmet Çağrı Aykan, Ezgi Kalaycıoğlu, İsmail Bolat, Onur Taşar, Özgen Şafak, Macit Kalçık and 6 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Anatolian journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02344901 (ReAl-life Multicentre Survey Evaluating the Status of Stroke Prevention Strategies in Patients With Non-Valvular Atrial Fibrillation in TurKey), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02344901 completednot on this map

ReAl-life Multicentre Survey Evaluating the Status of Stroke Prevention Strategies in Patients With Non-Valvular Atrial Fibrillation in TurKey (RAMSES)

Typeobservational_patient_registrySponsorMuğla Sıtkı Koçman UniversityRan2015 to 2015Enrolled6,273ConditionsThrombotic Stroke, Atrial Fibrillation and Flutter
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Anticoagulation Timing After Stroke in Atrial Fibrillation: Evidence from a Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Özcan BaşaranDepartment of Cardiology, Faculty of Medicine, Muğla Sıtkı Kocman University, Muğla-Turkey. basaran_ozcan@yahoo.com.
Osman BetonDepartment of Cardiology, Faculty of Medicine,Sivas Cumhuriyet University, Sivas-Turkey.
Volkan DoğanDepartment of Cardiology, Faculty of Medicine, Muğla Sıtkı Kocman University, Muğla-Turkey.
Mehmet TekinalpDepartment of Cardiology, Kahramanmaraş Necip Fazıl State Hospital, Kahramanmaraş-Turkey.
Ahmet Çağrı AykanDepartment of Cardiology, Trabzon Ahi Evren Chest Cardiovascular Surgery Education and Research Hospital, Trabzon-Turkey.
Ezgi KalaycıoğluDepartment of Cardiology, Trabzon Ahi Evren Chest Cardiovascular Surgery Education and Research Hospital, Trabzon-Turkey.
İsmail BolatDepartment of Cardiology, Fethiye State Hospital, Fethiye-Turkey.
Onur TaşarDepartment of Cardiology, Elazığ Education and Research Hospital, Elazığ-Turkey.
Özgen ŞafakDepartment of Cardiology, Burdur State Hospital, Burdur-Turkey.
Macit KalçıkDepartment of Cardiology, İskilip Atıf Hoca State Hospital, Çorum-Turkey.
Mehmet YamanDepartment of Cardiology, Samsun Education and Research Hospital, Samsun-Turkey.
İbrahim AltunDepartment of Cardiology, Faculty of Medicine, Muğla Sıtkı Kocman University, Muğla-Turkey.
Mustafa Özcan SoyluDepartment of Cardiology, Faculty of Medicine, Muğla Sıtkı Kocman University, Muğla-Turkey.
Cevat KırmaDepartment of Cardiology, Kartal Koşuyolu Heart Education and Research Hospital, İstanbul-Turkey.
Murat BitekerDepartment of Cardiology, Faculty of Medicine, Muğla Sıtkı Kocman University, Muğla-Turkey.
RAMSES Study
Muğla University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveData regarding stroke prevention strategies in non-valvular atrial fibrillation (NVAF) are limited to vitamin K antagonists (VKAs). This study aimed to evaluate real-life stroke prevention strategies for NVAF patients in the era of non-VKA oral anticoagulants (NOACs).

methodsWe established a cross-sectional, multicenter, nationwide registry of NVAF patients. All consecutive atrial fibrillation (AF) patients and without mechanical heart valves or rheumatic mitral stenosis (but including those with any degree of mitral regurgitation) were enrolled in the ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies (RAMSES Study; ClinicalTrials.gov identifier NCT02344901) in Turkey. Baseline demographic data, medical history, and medications prescribed for NVAF treatment were collected. Univariate analyses were performed for continuous variables, and the chi-square test was used for categorical variables.

resultsIn total, 6273 patients from 29 provinces of Turkey were enrolled in the study between February and May 2015, with the contribution of 83 investigators. The mean age was 69.6±10.7 years; 56% of the patients were females, and one-fifth of the patients had at least one comorbid disease, the most common being hypertension (69%). The mean CHA2DS2-VASc and HAS-BLED scores were 3.3±1.6 and 1.6±1.1, respectively. The rate of oral anticoagulant (OAC) therapy use was 72% (37% NOAC and 35% VKA).

conclusionThe RAMSES study showed a higher prevalence of OAC use among NVAF patients than that reported in previous studies. Although NOACs were preferred over VKAs in daily cardiology practice, there is a need for improved OAC therapies for NVAF patients.

Indexed as

Administration, OralAgedAged, 80 and overAnticoagulantsAtrial FibrillationCross-Sectional StudiesFemaleHumansMiddle AgedRisk FactorsStrokeSurveys and QuestionnairesTurkeyAnticoagulants

Identifiers

PMID27723665
PMCPMC5324932
OpenAlexW2340733325

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.