ArticleJournal of affective disorders2017
Longitudinal associations of hypersomnolence and depression in the Wisconsin Sleep Cohort Study.
Article in Journal of affective disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Association of sleep duration and risk of mental disorder: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Nocturnal sleep architecture in idiopathic hypersomnia: a systematic review and meta-analysis.Sleep medicine · 2018Pooled it
- Hypersomnolence in focus: a white paper of the 6th Think Tank World Sleep Forum.Sleep medicine · 2025Review
- Mood Disorders and Dysautonomia in Patients Diagnosed with Idiopathic Hypersomnia: A Retrospective Analysis (2000-2023).Journal of clinical medicine · 2025Article
- Pathophysiological Models of Hypersomnolence Associated With Depression.Biological psychiatry global open science · 2025Review
- The association between nap time, nighttime sleep and depression in Chinese older adults: A cross-sectional study.PloS one · 2024Article
- Polygenic predisposition, sleep duration, and depression: evidence from a prospective population-based cohort.Translational psychiatry · 2023Article
- Associations of sleep duration, daytime napping, and snoring with depression in rural China: a cross-sectional study.BMC public health · 2023Article
- Metabolic health disparities driven by financial stress: Behavioural adaptation or modification?Stress and health : journal of the International Society for the Investigation of Stress · 2023Article
- Relationship between depression, smartphone addiction, and sleep among Chinese engineering students during the COVID-19 pandemic.World journal of psychiatry · 2023Article
- Association between stressful life events and non-optimal lipid levels among women with hyperlipidaemia.European journal of cardiovascular nursing · 2023Article
- Elusive hypersomnolence in seasonal affective disorder: actigraphic and self-reported sleep in and out of depressive episodes.Psychological medicine · 2023Article
- Latent profile analysis of post-traumatic stress and post-traumatic growth among firefighters.European journal of psychotraumatology · 2023Article
- Associations between Insomnia, Daytime Sleepiness, and Depressive Symptoms in Adolescents: A Three-Wave Longitudinal Study.Journal of clinical medicine · 2022Article
- Central hypersomnia and chronic insomnia: expanding the spectrum of sleep disorders in long COVID syndrome - a prospective cohort study.BMC neurology · 2022Article
- The association between sleep and depressive symptoms in US adults: data from the NHANES (2007-2014).Epidemiology and psychiatric sciences · 2022Article
- Why Sleep is Key: Poor Sleep Quality is a Mechanism for the Bidirectional Relationship between Major Depressive Disorder and Generalized Anxiety Disorder Across 18 Years.Journal of anxiety disorders · 2022Article
- Impaired neurobehavioral alertness quantified by the psychomotor vigilance task is associated with depression in the Wisconsin Sleep Cohort study.Sleep medicine · 2020Article
- Excessive sleepiness and associated symptoms in the U.S. adult population: prevalence, correlates, and comorbidity.Sleep health · 2020Article
- Reported and Recorded Sleepiness in Obesity and Depression.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHypersomnolence is common in depression, however longitudinal associations of excessive daytime sleepiness (EDS), long habitual sleep duration, and objective sleep propensity with depressive symptomatology are not well established.
methodsData from adults participating in the Wisconsin Sleep Cohort Study who had multiple assessments at 4-year intervals were utilized in analyses. Conditional (intrasubject) logistic regression estimated the likelihood of development of depression and three primary hypersomnolence measures: subjective EDS [Epworth Sleepiness Scale (ESS) >10], habitual sleep duration ≥9h/day, and increased physiological sleep propensity [multiple sleep latency test (MSLT) mean sleep latency <8min].
resultsAfter adjusting for all covariates, the odds for development of depression were significantly increased 1.67-fold (95% CI 1.02-2.73, p=0.04) in participants who also developed subjective EDS. However, development of increased physiological sleep propensity on the MSLT was associated with a trend towards reduced odds for development of depression (odds ratio 0.50, 95% CI 0.24-1.06, p=0.07). No significant longitudinal association between excessive sleep duration and depression was observed. LIMITATIONS: Depression was not verified by psychiatric interview and an objective measure of sleep duration was not utilized.
conclusionsOur results demonstrate a significant longitudinal association between increased subjective EDS and depression. However, increased physiological sleep propensity on the MSLT was paradoxically marginally protective against the development of depression. Further research is indicated to determine the mechanism underling divergent effects of various aspects of hypersomnolence on the course of mood disorders.
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