Evidence map›Paper›PMID 27723176›Full record

ReviewReviews in medical virology2017

Saffold virus, an emerging human cardiovirus.

Shawn Zheng Kai Tan, Mark Zheng Yi Tan, Mookkan Prabakaran

Open access · bronzeAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. ITAFProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Ovalbumin-specific CD4Frontiers in immunology · 2023
    Article
  9. Blood virosphere in febrile Tanzanian children.Emerging microbes & infections · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Saffold virus, an emerging human cardiovirus.Reviews in medical virology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shawn Zheng Kai TanTemasek Life Science Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore.ORCID 0000-0001-7258-9596
Mark Zheng Yi TanCritical Care Unit, Central Manchester Foundation NHS Trust, Manchester, UK.
Mookkan PrabakaranTemasek Life Science Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore.
Temasek Life Sciences Laboratory · SGManchester University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saffold virus (SAFV) is an emerging human cardiovirus that has been shown to be ubiquitous. Initial studies of SAFV focused on respiratory and gastrointestinal infection; however, it has also recently been associated with diverse clinical symptoms including the endocrine, cardiovascular, and neurological systems. Given the systemic nature of SAFV, and its high prevalence, understanding its pathogenicity and clinical impact is of utmost importance. This comprehensive review highlights and discusses recent developments in epidemiology, human pathogenicity, animal, and molecular studies related to SAFV. It also provides detailed insights into the neuropathogenicity of SAFV. We argue that human studies have been confounded by coinfections and therefore require support from robust molecular and animal research. Thereby, we aim to provide foresight into further research to better understand this emerging virus.

Indexed as

AnimalsCardiovirus InfectionsCommunicable Diseases, EmergingDisease Models, AnimalHumansPrevalenceTheilovirusanimal modelCNSneurotropicpathogenicitySaffold virus

Identifiers

PMID27723176
PMCPMC7169152
OpenAlexW2531349698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.