ArticleJournal of gastroenterology2017
Autoimmune hepatitis in Japan: trends in a nationwide survey.
Article in Journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 67 citations in OpenAlex.
- A case of acute autoimmune hepatitis complicated by autoimmune neutropenia and autoimmune hemolytic anemia.Clinical journal of gastroenterology · 2026Article
- Identification of anti-DOK2 antibodies in patients with autoimmune hepatitis via a human protein microarray.Hepatology communications · 2025Article
- Autoimmune Hepatitis and Drug-Induced Liver Injury in Japan.Journal of clinical medicine · 2025Review
- Clinicopathological characteristics of autoimmune‑like hepatitis after drug‑induced liver injury.Biomedical reports · 2025Article
- Autoimmune Hepatitis with Metabolic Dysfunction-associated Fatty Liver Disease.Internal medicine (Tokyo, Japan) · 2025Article
- Advances in the Treatment of Autoimmune Hepatitis.Journal of clinical and translational hepatology · 2024Review
- Acute presentation of autoimmune hepatitis -from acute hepatitis to ALF and ACLF.Hepatology international · 2024Review
- Evaluation of the histological scoring systems of autoimmune hepatitis: A significant step towards the optimization of clinical diagnosis.Clinical and molecular hepatology · 2024Article
- Accuracy of controlled attenuation parameter measurement for the detection of steatosis in autoimmune liver diseases.JHEP reports : innovation in hepatology · 2023Article
- Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients.Canadian journal of gastroenterology & hepatology · 2022Article
- Prognosis of probable autoimmune hepatitis patients: a single-center study in Japan.Internal and emergency medicine · 2021Article
- The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis.Hepatology international · 2021Article
- Differences in autoimmune hepatitis based on inflammation localization.Medical molecular morphology · 2021Article
- Clinical characteristics and treatment outcomes of acute severe autoimmune hepatitis.BMC gastroenterology · 2021Article
- Dysfunctional Immune Regulation in Autoimmune Hepatitis: From Pathogenesis to Novel Therapies.Frontiers in immunology · 2021Review
- Recent updates on the management of autoimmune hepatitis.Clinical and molecular hepatology · 2021Review
- Programmed cell death-1Journal of translational autoimmunity · 2021Article
- Development of anti-centromere antibody-positive autoimmune hepatitis after childbirth.Clinical journal of gastroenterology · 2020Article
- Autoimmune Hepatitis: 2019 Update.Gut and liver · 2020Review
- Article
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Authors and funding
16 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA nationwide survey of autoimmune hepatitis (AIH) patients was performed in Japan in 2015. The aims of this study were to elucidate the trends and characteristics of AIH in Japan, in addition to identifying differences in AIH between acute hepatitis and chronic hepatitis.
methodsQuestionnaires about patients with AIH diagnosed from 2009 to 2013 were sent to 437 hospitals or clinics with hepatology specialists.
resultsA total of 1682 patients were enrolled. The mean age at diagnosis was 60.0 years, and 87.1 % of patients were female. Serum immunoglobulin G levels were high, peaking at 1.5-2.0 g/dL. Histological diagnoses of chronic hepatitis, acute hepatitis, and cirrhosis were seen in 79.6, 11.7, and 6.7 % of patients respectively. In addition to elevation of aminotransferase levels, the frequencies of emperipolesis and human leukocyte antigen (HLA)-DR2 positivity were higher in patients with acute hepatitis than in those with chronic hepatitis. Approximately 80 % of patients were treated with corticosteroids, and in 97.7 % of them, their condition improved. Steroid pulse therapy was more frequently given to patients with acute hepatitis than to those with chronic hepatitis.
conclusionsIn the present nationwide survey of AIH patients in Japan, patients with acute hepatitis had clinical features different from those of patients with chronic hepatitis.
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