Evidence map›Paper›PMID 27722926›Full record

ArticleMolecular neurobiology2017

MPP

Mauricio P Cunha, Francis L Pazini, Vicente Lieberknecht, Josiane Budni, Ágatha Oliveira, Júlia M Rosa, Gianni Mancini, Leidiane Mazzardo, André R Colla, Marina C Leite and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Atractylenolide-I Attenuates MPTP/MPPNeurochemical research · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. MiR-193b deregulation is associated with Parkinson's disease.Journal of cellular and molecular medicine · 2021
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Mauricio P CunhaDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil. mauricio.personal@gmail.com.
Francis L PaziniDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Vicente LieberknechtDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Josiane BudniLaboratory of Neurosciences, National Institute for Translational Medicine, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Ágatha OliveiraDepartment of Biochemistry, Institute of Chemistry, Universidade de São Paulo, São Paulo, SP, 05508-900, Brazil.
Júlia M RosaDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Gianni ManciniDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Leidiane MazzardoDepartment of Morphological Sciences, Center of Biological Science, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
André R CollaCentro Universitário Municipal de São José, São José, SC, Brazil.
Marina C LeiteDepartment of Biochemistry, Institute of Basic Health Science, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2600-Anexo, Porto Alegre, Rio Grande do Sul, 90035-003, Brazil.
Adair R S SantosDepartment of Physiological Sciences, Center of Biological Science, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Daniel F MartinsGraduate Program in Health Sciences, Universidade do Sul de Santa Catarina, Pedra Branca, Palhoça, SC, 88137-270, Brazil.
Andreza F de BemDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Carlos Alberto S GonçalvesDepartment of Biochemistry, Institute of Basic Health Science, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2600-Anexo, Porto Alegre, Rio Grande do Sul, 90035-003, Brazil.
Marcelo FarinaDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Ana Lúcia S RodriguesDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Universidade Federal de Santa Catarina · BRUniversidade Federal do Rio Grande do Sul · BRCentro Universitário Municipal de São José · BRMorpho (United States) · USUniversidade de São Paulo · BRUniversidade do Extremo Sul Catarinense · BRUniversidade do Sul de Santa Catarina · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) #308723/2013-9Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) #449436/2014-4NENASC Project (PRONEX-FAPESC/CNPq) 1262/2012-9Rede Instituto Brasileiro de Neurociências (IBN-Net/CNPq) 01.06.0842-00Science Without Borders funding programme [Programa Ciência Sem Fronteiras/Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 403120/2012-8
6 · The paper itself

Abstract

The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces motor and nonmotor dysfunctions resembling Parkinson's disease (PD); however, studies investigating the effects of 1-methyl-4-phenylpyridinium (MPP

Indexed as

1-Methyl-4-phenylpyridiniumAcetylcholinesteraseAnimalsCorpus StriatumEmotionsGlial Fibrillary Acidic ProteinGlutathioneLearningMemoryMiceMotor ActivityS100 Calcium Binding Protein beta SubunitThiobarbituric Acid Reactive Substances1-Methyl-4-phenylpyridiniumAcetylcholinesteraseGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mouseGlutathioneS100b protein, mouseS100 Calcium Binding Protein beta SubunitThiobarbituric Acid Reactive SubstancesGliaMPP+Neurotrophic factorsOxidative stressParkinson’s disease

Identifiers

PMID27722926
OpenAlexW2529847745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.