ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017
Serial optical coherence tomography angiography for corneal vascularization.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Optical coherence tomography angiography in evaluating the response of ocular surface squamous neoplasia to topical immunotherapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Advanced imaging of corneal neovascularisation with a novel swept-source AS-OCTA system.The British journal of ophthalmology · 2025Observational
- Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface.Medicina (Kaunas, Lithuania) · 2024Review
- Superficial ocular vascular changes after orbital decompression in patients with thyroid ophthalmopathy measured by anterior segment OCT angiography; an observational study.Scientific reports · 2024Observational
- Current clinical applications of anterior segment optical coherence tomography angiography: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
- A comprehensive update on the use of optical coherence tomography angiography in glaucoma.International ophthalmology · 2023Review
- A two-stage framework for optical coherence tomography angiography image quality improvement.Frontiers in medicine · 2023Article
- Automated Image Threshold Method Comparison for Conjunctival Vessel Quantification on Optical Coherence Tomography Angiography.Translational vision science & technology · 2022Article
- Role of Anterior Segment-Optical Coherence Tomography Angiography in Acute Ocular Burns.Diagnostics (Basel, Switzerland) · 2022Review
- Optical coherence tomography angiography in herpetic leucoma.BMC medical imaging · 2022Article
- Novel Parameters to Assess the Severity of Corneal Neovascularization Using Anterior Segment Optical Coherence Tomography Angiography.American journal of ophthalmology · 2021Observational
- A pilot study investigating anterior segment optical coherence tomography angiography as a non-invasive tool in evaluating corneal vascularisation.Scientific reports · 2021Article
- Advances and Current Clinical Applications of Anterior Segment Optical Coherence Tomography Angiography.Frontiers in medicine · 2021Review
- Role of optical coherence tomography angiography in the characterization of vascular network patterns of ocular surface squamous neoplasia.The ocular surface · 2020Article
- Article
- A Review of Imaging Biomarkers of the Ocular Surface.Eye & contact lens · 2020Review
- Optical Coherence Tomography Angiography Evaluation of Conjunctival Vessels During Filtering Surgery.Translational vision science & technology · 2019Article
- Optical coherence tomography angiography in diabetic retinopathy: a review of current applications.Eye and vision (London, England) · 2019Review
- Optical coherence tomography angiography for the anterior segment.Eye and vision (London, England) · 2019Review
- Vessel density and En-face segmentation of optical coherence tomography angiography to analyse corneal vascularisation in an animal model.Eye and vision (London, England) · 2019Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRecently, optical coherence tomography angiography (OCTA) has been used to successfully delineate vessels within the retina. This current study aims to assess corneal vascularization secondary to herpetic keratitis pre- and post-treatment using serial OCTA imaging adapted for the anterior segment.
methodsAll eyes were scanned using the split-spectrum amplitude decorrelation angiography (SSADA) algorithm on the AngioVue OCTA system (Optovue Inc. Fremont, CA, USA) with an anterior segment lens adapter. Multiple scans in the regions of interest (ROI) before and after treatment were analysed to assess change in corneal vascularization in response to each treatment modality.
resultsWe analyzed a total of 12 OCTA scans in three eyes with corneal vascularization, comparing images pre- and 3 months post-treatment. We found that the OCTA was able to detect a significant decrease in area of vascularization in all eyes: including fine-needle diathermy (48 ± 7 to 41 ± 5 %, P = 0.048), subconjunctival bevacizumab (45 ± 7 to 38 ± 5 %, P = 0.015) and systemic steroid treatment following graft rejection (38 ± 1 to 32 ± 2 %, P = 0.003).
conclusionsOur preliminary study of serial OCTA scans suggests that this may be a useful tool for objective quantification of corneal vascularization. Future development of image processing software will be needed for clinical use or trials to evaluate anti-vascular therapies.
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