Evidence map›Paper›PMID 27722554›Full record

ArticleSoft matter2016

Membrane stiffness is modified by integral membrane proteins.

Philip W Fowler, Jean Hélie, Anna Duncan, Matthieu Chavent, Heidi Koldsø, Mark S P Sansom

Open access · hybridAbstract read
In one paragraph

Article in Soft matter, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
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  8. The Role of Cholesterol in M2 Clustering and Viral Budding Explained.Journal of chemical theory and computation · 2025
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  11. Valency of Ligand-Receptor Binding from Pair Potentials.Journal of chemical theory and computation · 2024
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  14. Review
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  17. Article
  18. Article
  19. Article
  20. Extracellular vesicle-matrix interactions.Nature reviews. Materials · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Philip W FowlerDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.ORCID http://orcid.org/0000-0003-0912-4483
Jean HélieDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.
Anna DuncanDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.
Matthieu ChaventDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.
Heidi KoldsøDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.
Mark S P SansomDepartment of Biochemistry, University of Oxford, South Parks Rd, Oxford, OX1 3QU, UK. mark.sansom@bioch.ox.ac.uk.
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I019855/1Wellcome Trust
6 · The paper itself

Abstract

The ease with which a cell membrane can bend and deform is important for a wide range of biological functions. Peripheral proteins that induce curvature in membranes (e.g. BAR domains) have been studied for a number of years. Little is known, however, about the effect of integral membrane proteins on the stiffness of a membrane (characterised by the bending rigidity, K

Indexed as

Cell MembraneComputer SimulationLipid BilayersMembrane ProteinsMolecular Dynamics SimulationPhosphatidylcholinesLipid BilayersMembrane ProteinsPhosphatidylcholines

Identifiers

PMID27722554
PMCPMC5314686
OpenAlexW2511167907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.